O
Ohgew Kweon
Researcher at Food and Drug Administration
Publications - 41
Citations - 1573
Ohgew Kweon is an academic researcher from Food and Drug Administration. The author has contributed to research in topics: Mycobacterium vanbaalenii & Pyrene. The author has an hindex of 18, co-authored 41 publications receiving 1354 citations. Previous affiliations of Ohgew Kweon include University of Arkansas at Little Rock & National Center for Toxicological Research.
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Journal ArticleDOI
Complete and Integrated Pyrene Degradation Pathway in Mycobacterium vanbaalenii PYR-1 Based on Systems Biology
TL;DR: Analysis of pyrene metabolism in M. vanbaalenii PYR-1 indicates that this bacterium degrades pyrene to central intermediates through o-phthalate and the beta-ketoadipate pathway.
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Molecular cloning and expression of genes encoding a novel dioxygenase involved in low- and high-molecular-weight polycyclic aromatic hydrocarbon degradation in Mycobacterium vanbaalenii PYR-1.
Seong-Jae Kim,Ohgew Kweon,James P. Freeman,Richard C. Jones,Michael D. Adjei,Jin-Woo Jhoo,Ricky D. Edmondson,Carl E. Cerniglia +7 more
TL;DR: The upregulation of nidA3B3 in M. vanbaalenii PYR-1 induced by PAHs was confirmed by reverse transcription-PCR analysis and close similarities to the corresponding PAH ring-hydroxylating dioxygenases from Mycobacterium and Rhodococcus were revealed.
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A new classification system for bacterial Rieske non-heme iron aromatic ring-hydroxylating oxygenases
Ohgew Kweon,Seong-Jae Kim,Songjoon Baek,Jong-Chan Chae,Michael D. Adjei,Dong-Heon Baek,Young-Chang Kim,Carl E. Cerniglia +7 more
TL;DR: A scheme for classification of RHOs reflecting new sequence information and interactions between RHO enzyme components and provides new insights into the evolution of RHO systems based on enzyme interaction is presented.
Journal ArticleDOI
Genomic analysis of polycyclic aromatic hydrocarbon degradation in Mycobacterium vanbaalenii PYR-1.
Seong-Jae Kim,Ohgew Kweon,Richard C. Jones,Ricky D. Edmondson,Ricky D. Edmondson,Carl E. Cerniglia +5 more
TL;DR: A pathway in which HMW PAHs are degraded into the β-ketoadipate pathway through protocatechuate and then mineralized to CO2 via TCA cycle is proposed and identified 67 and 23 genes involved in PAH degradation and T CA cycle pathways, respectively, to be expressed as proteins.
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Molecular Characterization of Resistance to Extended-Spectrum Cephalosporins in Clinical Escherichia coli Isolates from Companion Animals in the United States
Bashar W. Shaheen,Rajesh Nayak,Steven L. Foley,Ohgew Kweon,Joanna Deck,Miseon Park,Fatemeh Rafii,Dawn M. Boothe +7 more
TL;DR: This study shows the emergence of conjugative plasmid-borne ESBLs among E. coli strains from companion animals in the United States, which may compromise the effective therapeutic use of ESCs in veterinary medicine.