O
Oliver Patschan
Researcher at Lund University
Publications - 31
Citations - 1683
Oliver Patschan is an academic researcher from Lund University. The author has contributed to research in topics: Bladder cancer & Cystectomy. The author has an hindex of 15, co-authored 31 publications receiving 1366 citations.
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Journal ArticleDOI
A Molecular Taxonomy for Urothelial Carcinoma
Gottfrid Sjödahl,Martin Lauss,Kristina Lövgren,Gunilla Chebil,Sigurdur Gudjonsson,Srinivas Veerla,Oliver Patschan,Mattias Aine,Mårten Fernö,Markus Ringnér,Wiking Månsson,Fredrik Liedberg,David Lindgren,Mattias Höglund +13 more
TL;DR: The molecular subtypes cut across pathologic classification, and class-defining gene signatures show coordinated expression irrespective of pathologic stage and grade, suggesting the molecular phenotypes as intrinsic properties of the tumors.
Journal ArticleDOI
Integrated genomic and gene expression profiling identifies two major genomic circuits in urothelial carcinoma.
David Lindgren,Gottfrid Sjödahl,Martin Lauss,Johan Staaf,Gunilla Chebil,Kristina Lövgren,Sigurdur Gudjonsson,Fredrik Liedberg,Oliver Patschan,Wiking Månsson,Mårten Fernö,Mattias Höglund +11 more
TL;DR: The integrative approach revealed at least two separate networks of genomic alterations linked to the molecular diversity seen in UC, and that these circuits may reflect distinct pathways of tumor development.
Journal ArticleDOI
Toward a Molecular Pathologic Classification of Urothelial Carcinoma
Gottfrid Sjödahl,Kristina Lövgren,Martin Lauss,Oliver Patschan,Sigurdur Gudjonsson,Gunilla Chebil,Mattias Aine,Pontus Eriksson,Wiking Månsson,David Lindgren,Mårten Fernö,Fredrik Liedberg,Mattias Höglund +12 more
TL;DR: A simple IHC/histology-based classifier is presented that is easy to implement as a standard pathologic evaluation to differentiate the three major subtypes: urobasal, genomically unstable, and SCCL, which exhibit important prognostic differences.
Journal ArticleDOI
A Molecular Pathologic Framework for Risk Stratification of Stage T1 Urothelial Carcinoma
Oliver Patschan,Gottfrid Sjödahl,Gunilla Chebil,Kristina Lövgren,Martin Lauss,Sigurdur Gudjonsson,Petter Kollberg,Pontus Eriksson,Mattias Aine,Wiking Månsson,Mårten Fernö,Fredrik Liedberg,Mattias Höglund +12 more
TL;DR: Classification of stage T1 urothelial carcinoma into molecular subtypes can improve the identification of patients with progressing tumours and is shown to improve progression-free survival.
Journal ArticleDOI
Infiltration of CD3(+) and CD68(+) cells in bladder cancer is subtype specific and affects the outcome of patients with muscle-invasive tumors.
Gottfrid Sjödahl,Kristina Lövgren,Martin Lauss,Gunilla Chebil,Oliver Patschan,Sigurdur Gudjonsson,Wiking Månsson,Mårten Fernö,Karin Leandersson,David Lindgren,Fredrik Liedberg,Mattias Höglund +11 more
TL;DR: The presence of infiltrating CD3(+) TILs was significantly associated with good prognosis in the MI cases and the strongest association with poor survival was observed for a high ratio between CD68 and CD3 (P = 7×10(-5).