O
Oludare A. Odumade
Researcher at Boston Children's Hospital
Publications - 25
Citations - 2229
Oludare A. Odumade is an academic researcher from Boston Children's Hospital. The author has contributed to research in topics: Medicine & Cytotoxic T cell. The author has an hindex of 11, co-authored 18 publications receiving 1881 citations. Previous affiliations of Oludare A. Odumade include University of London & University of Minnesota.
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Journal ArticleDOI
Normalizing the environment recapitulates adult human immune traits in laboratory mice
Lalit K. Beura,Sara E. Hamilton,Kevin Bi,Jason M. Schenkel,Oludare A. Odumade,Kerry A. Casey,Emily A. Thompson,Kathryn A. Fraser,Pamela C. Rosato,Ali Filali-Mouhim,Rafick Pierre Sekaly,Marc K. Jenkins,Vaiva Vezys,W. Nicholas Haining,Stephen C. Jameson,David Masopust +15 more
TL;DR: It is shown that standard laboratory mouse husbandry has profound effects on the immune system and that environmental changes produce mice with immune systems closer to those of adult humans, and suggested that restoring physiological microbial exposure in laboratory mice could provide a relevant tool for modelling immunological events in free-living organisms, including humans.
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Progress and Problems in Understanding and Managing Primary Epstein-Barr Virus Infections
TL;DR: The biology of EBV and the host immune response are described and the characteristics and pathogenesis of infectious mononucleosis are discussed in the context of developing therapeutic and preventative strategies.
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Behavioral, Virologic, and Immunologic Factors Associated With Acquisition and Severity of Primary Epstein–Barr Virus Infection in University Students
Henry H. Balfour,Oludare A. Odumade,David O. Schmeling,Beth D. Mullan,Julie A. Ed,Jennifer A. Knight,Heather E. Vezina,William Thomas,Kristin A. Hogquist +8 more
TL;DR: Kissing was a significant risk for primary EBV infection, a total of 89% of infections were symptomatic, and blood viral load and CD8(+) lymphocytosis correlated with disease severity, according to university students studied prospectively.
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T cells expressing the transcription factor PLZF regulate the development of memory-like CD8+ T cells.
TL;DR: It is shown that the same mechanism drove the differentiation of innate CD8+ T cells in BALB/c mice and was also attributable to this IL-4-dependent mechanism.
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The proapoptotic function of Noxa in human leukemia cells is regulated by the kinase Cdk5 and by glucose.
Xazmin Lowman,Maureen A. McDonnell,Ashley Kosloske,Oludare A. Odumade,Christopher Jenness,Christine B. Karim,Ronald Jemmerson,Ameeta Kelekar +7 more
TL;DR: It is proposed that Noxa plays both growth-promoting and proapoptotic roles in hematopoietic cancers with phospho-S(13) as the glucose-sensitive toggle switch controlling these opposing functions.