O
Oluyinka O. Olutoye
Researcher at VCU Medical Center
Publications - 9
Citations - 639
Oluyinka O. Olutoye is an academic researcher from VCU Medical Center. The author has contributed to research in topics: Wound healing & Platelet. The author has an hindex of 8, co-authored 9 publications receiving 622 citations.
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Journal ArticleDOI
Ability of chronic wound fluids to degrade peptide growth factors is associated with increased levels of elastase activity and diminished levels of proteinase inhibitors.
Dorne R. Yager,Stephen M. Chen,Susan I. Ward,Oluyinka O. Olutoye,Robert F. Diegelmann,I. Kelman Cohen +5 more
TL;DR: The ability of some chronic nonhealing wounds to rapidly degrade exogenously added growth factors has important implications with regard to past and future clinical attempts to use peptide growth factors to treat these types of problem wounds.
Journal ArticleDOI
Interleukin-1alpha and collagenase activity are elevated in chronic wounds
Eleanor J Barone,Dorne R. Yager,A L Pozez,Oluyinka O. Olutoye,M C Crossland,Robert F. Diegelmann,I K Cohen +6 more
TL;DR: As the chronic wounds began to heal, there was a significant decrease in the IL-1alpha levels and collagenase activity, thus suggesting that these two proteins may contribute to the lack of healing characteristic of chronic wounds.
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Lower cytokine release by fetal porcine platelets: A possible explanation for reduced inflammation after fetal wounding
TL;DR: Although no gross differences in platelet ultrastructure were noted, fetal porcine platelets release lower quantities of cytokines into serum, which may explain, in part, the minimal inflammation and sparse fibrosis characteristic of fetal wounds.
Journal ArticleDOI
Hyaluronic acid inhibits fetal platelet function: Implications in scarless healing
Oluyinka O. Olutoye,Eleanor J Barone,Dorne R. Yager,Takashi Uchida,I. Kelman Cohen,Robert F. Diegelmann +5 more
TL;DR: It is concluded that HA, the predominant GAG in fetal dermal matrix, inhibits platelet aggregation and cytokine release and thus contributes to the minimal scarring characteristic of fetal tissue repair.
Journal ArticleDOI
Aggregatory characteristics and expression of the collagen adhesion receptor in fetal porcine platelets
Oluyinka O. Olutoye,Samuel M. Alaish,Marcus E. Carr,Moohyun Paik,Dorne R. Yager,I. Kelman Cohen,Robert F. Diegelmann +6 more
TL;DR: There is a transition to "adultlike" platelet aggregatory activity in the third trimester, which correlates with the period of transition to adultlike wound healing in utero.