Ozden Sanal

TL;DR: The results suggest that CD3γ contributes to, but is not absolutely required for, the regulation of TCR trafficking in resting and Ag-stimulated mature T lymphocytes, and indicates that TCR internalization is regulated differently in each case.

TL;DR: F fused fibroblasts of a recently identified MHC class II deficiency patient, OSE, with fibro Blasts derived from patients representative of each of the four complementation groups, finding that OSE was homozygous for the splice site mutation.

TL;DR: Ataxia telangiectasia homozygotes have an increased risk for development of Hodgkin's disease (HD), and of 6 AT patients in the HD series, 3 developed pulmonary cavities.

TL;DR: The activities of the enzymes involved in cellular antioxidant metabolism in A-T patients were determined to see if there is any defect which may result in constant oxidative stress and superoxide dismutase and catalase activities of erythrocytes, in contrast to lymphocytes, were found to be significantly higher in patients than in healthy controls.

TL;DR: An alloBMT from an HLA-identical sibling donor on a 4-year-old girl who presented in accelerated phase with neurological manifestations including convulsions, strabismus, severe dysarthria, ataxia and clonus is carried out and long-term follow-up will determine the prognosis regarding the neurological findings.