P
P. M. E. Altham
Researcher at University of Cambridge
Publications - 29
Citations - 2654
P. M. E. Altham is an academic researcher from University of Cambridge. The author has contributed to research in topics: Contingency table & Psychopathology. The author has an hindex of 22, co-authored 29 publications receiving 2586 citations.
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Recent life events, cortisol, dehydroepiandrosterone and the onset of major depression in high-risk adolescents.
TL;DR: A subgroup of adolescents may carry a physiological risk for major depression which may be either of genetic and/or earlier psychosocial origin.
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Adrenal secretion during major depression in 8- to 16-year-olds, I. Altered diurnal rhythms in salivary cortisol and dehydroepiandrosterone (DHEA) at presentation.
TL;DR: In this article, the association between basal cortisol, dehydroepiandrosterone (DHEA), its sulphate, and major depression was investigated in 8- to 16-year-olds.
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Two Generalizations of the Binomial Distribution
TL;DR: In this article, the sum of k independent and identically distributed (0, 1) variables has a binomial distribution and two distinct generalizations are obtained, depending on whether the "multiplicative" or "additive" definition of interaction for discrete variables is used.
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Adrenal steroid secretion and major depression in 8- to 16-year-olds, III. Influence of cortisol/DHEA ratio at presentation on subsequent rates of disappointing life events and persistent major depression
TL;DR: The finding that it is depressed subjects with high cortisol/DHEA ratios at presentation who are specifically at risk for subsequent disappointing life events suggests a putative role for these adrenal steroids in abnormal cognitive or emotional processes associated with disturbed interpersonal behaviour.
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First-episode major depression in adolescents. Affective, cognitive and endocrine characteristics of risk status and predictors of onset.
TL;DR: Both negative mood and feelings and alterations in adrenal steroid function precede the onset of first-episode major depression in adolescents andVariation in levels of hormones may arise from more distal origins than recent life events and current ongoing difficulties.