P. Michael Conn

TL;DR: The results suggest that a pure antagonist becomes an agonist when it is capable of bringing two receptor molecules within a critical distance, d, and indicate that formation of the receptor microaggregate itself is sufficient to stimulate a transmembrane response system.

TL;DR: Cytology and Organization of Cell Types: Light and Electron Microscopy Rochelle S. Cohen and Donald W. Pfaff Anatomy of the Spinal Cord and Brain Bruce E. Maley Ion Channels and Electrical Signaling Stanko S. Stojilkovic and Robert L. Rodnitzky Synaptic Transmission Henrique vonGersdorf Pre- and Post-Synaptic Receptors Robert D. Grubbs Neuroembryology and Neurogenesis

TL;DR: GnRH and its analogs also have direct actions on the gonads in some species by inhibiting steroidogenesis in males and ovulation in females, and it is unlikely that hypothalamic-derived GnRH is responsible for these actions (because of the very low concentrations in the peripheral circulations).

TL;DR: Animal Models for the Study of Human Disease identifies important animal models and assesses the advantages and disadvantages of each model for the study of human disease, covering a broad range of animal models used in research for human disease.