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P. T. Perumal

Researcher at Central Leather Research Institute

Publications -  60
Citations -  1228

P. T. Perumal is an academic researcher from Central Leather Research Institute. The author has contributed to research in topics: Catalysis & Reagent. The author has an hindex of 19, co-authored 60 publications receiving 1114 citations.

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Facile one-pot synthesis of novel dispirooxindole-pyrrolidine derivatives and their antimicrobial and anticancer activity against A549 human lung adenocarcinoma cancer cell line.

TL;DR: Novel dispirooxindole-pyrrolidine derivatives have been synthesized through 1,3-dipolar cycloaddition of an azomethine ylide generated from isatin and sarcosine with the dipolarophile 3-(1H-indol-3-yl)-3-Oxo-2-(2-oxoindolin- 3-ylidene)propanenitrile, and also spiro compound of acenaphthene
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Novel spirooxindole-pyrrolidine compounds: synthesis, anticancer and molecular docking studies.

TL;DR: These spirooxindole-pyrrolidine compounds can be promising therapeutic agents for A549 lung adenocarcinoma cancer cell line.
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Oxidative cyclization of thiophenolic and phenolic Schiff's bases promoted by PCC: a new oxidant for 2-substituted benzothiazoles and benzoxazoles

TL;DR: Pyridinium chlorochromate (PCC) supported on silica gel effects the oxidative cyclization of structurally diverse thiophenolic and phenolic Schiff's bases, thereby providing an efficient and convenient method for the synthesis of a library of 2-arylbenzothiazoles.
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Synthesis, antibacterial activity evaluation and QSAR studies of novel dispiropyrrolidines.

TL;DR: Topology, shape, charge distribution and hydrophobic nature of the molecules had pronounced effect on the antibacterial activity of these dispiropyrrolidines.
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Synthesis, antimicrobial and antioxidant evaluation of quinolines and bis(indolyl)methanes.

TL;DR: An improved and practical synthesis of substituted quinolines and bis(indolyl)methanes was achieved under microwave condition using Zn(OTf)(2) as catalyst.