P
P. Thirugnanasambantham
Researcher at Madras Medical College
Publications - 17
Citations - 315
P. Thirugnanasambantham is an academic researcher from Madras Medical College. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 8, co-authored 13 publications receiving 301 citations.
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Journal ArticleDOI
Antinociceptive, anti-inflammatory and antipyretic effects of ethanol extract of Clerodendron serratum roots in experimental animals.
TL;DR: The alcoholic extract of Clerodendron serratum roots produced a significant antinociceptive, anti-inflammatory and antipyretic activities in animal models, which support the traditional claims of C. Serratum as a remedy for pain, inflammation and fever.
Journal ArticleDOI
A pyridine alkaloid from Ceropegia juncea
N.A. Adibatti,P. Thirugnanasambantham,C. Kulothungan,S. Viswanathan,Lalitha Kameswaran,K. Balakrishna,Ethirajan Sukumar +6 more
TL;DR: Cerpegin, a new pyridine alkaloid, has been isolated from Ceropegia juncea together with lupeol as discussed by the authors, based on spectroscopic methods.
Journal ArticleDOI
Analgesic activity of certain flavone derivatives: A structure-activity study
P. Thirugnanasambantham,S. Viswanathan,C. Mythirayee,V. Krishnamurty,Santa Ramachandran,Lalitha Kameswaran +5 more
TL;DR: A definite structure-activity relationship was observed in the analgesic activity of flavone derivatives as well as in their mechanism of action.
Journal Article
Pharmacological actions of cerpegin, a novel pyridine alkaloid from Ceropegia juncea
Ethirajan Sukumar,R. Hamsaveni Gopal,R. Bhima Rao,S. Viswanathan,P. Thirugnanasambantham,V. Vijayasekaran +5 more
TL;DR: Cerpegin, a novel furopyridine alkaloid isolated from the plant, showed no antibacterial activity against a few gram-positive and gram-negative organisms tested and did not show any antiviral activity against HIV.
Journal ArticleDOI
Analgesic activity of certain flavone derivatives: a structure‐activity study
P. Thirugnanasambantham,S. Viswanathan,S. Ramaswamy,V. Krishnamurty,C. Mythirayee,Lalitha Kameswaran +5 more
TL;DR: Flavone, its methoxy derivatives and flavanone were synthesized by standard methods and were tested for analgesic activity in mice by employing acetic acid writhing and tail flick methods.