P
P.V. Jonsson
Researcher at Leiden University Medical Center
Publications - 11
Citations - 429
P.V. Jonsson is an academic researcher from Leiden University Medical Center. The author has contributed to research in topics: Vitamin D and neurology & Dementia. The author has an hindex of 6, co-authored 11 publications receiving 311 citations. Previous affiliations of P.V. Jonsson include National Institutes of Health.
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Journal ArticleDOI
Space and location of cerebral microbleeds, cognitive decline, and dementia in the community
Jie Ding,Sigurður Sigurðsson,P.V. Jonsson,Gudny Eiriksdottir,Osorio Meirelles,Olafur Kjartansson,Oscar L. Lopez,Mark A. van Buchem,Vilmundur Gudnason,Lenore J. Launer +9 more
TL;DR: Findings suggest a role for hypertensive vasculopathy and the combined effect of hypertensive and cerebral amyloid angiopathy in the pathogenesis of cognitive deterioration in older people.
Journal ArticleDOI
Muscle Quality and Myosteatosis: Novel Associations With Mortality Risk The Age, Gene/Environment Susceptibility (AGES)-Reykjavik Study
Ilse Reinders,Rachel A. Murphy,Ingeborg A. Brouwer,Marjolein Visser,Lenore J. Launer,Kristin Siggeirsdottir,Gudny Eiriksdottir,Vilmundur Gudnason,P.V. Jonsson,Thomas Lang,Tamara B. Harris +10 more
TL;DR: In this article, the authors evaluated associations of thigh muscle composition, determined using computed tomography imaging, and knee extension strength with mortality risk among 4,824 participants aged 76.4 (standard deviation (SD), 5.5) years from the Age, Gene/Environment Susceptibility (AGES)-Reykjavik Study (2002-2006).
Featured Article Blood metabolite markers of preclinical Alzheimer's disease in two longitudinally followed cohorts of older individuals
Ramon Casanova,Sudhir Varma,Brittany Simpson,Min Kim,Yang An,Santiago Saldana,Carlos Riveros,Pablo Moscato,Michael Griswold,Denise Sonntag,Judith Wahrheit,Kristaps Klavins,P.V. Jonsson,Gudny Eiriksdottir,Thor Aspelund,Lenore J. Launer,Vilmundur Gudnason,Cristina Legido Quigley,Madhav Thambisetty +18 more
TL;DR: Recently, quantitative metabolomics identified a panel of 10 plasma lipids that were highly predictive of conversion to Alzheimer's disease (AD) in cognitively normal older individuals.
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Incidence of Brain Infarcts, Cognitive Change, and Risk of Dementia in the General Population: The AGES-Reykjavik Study (Age Gene/Environment Susceptibility-Reykjavik Study).
Sigurdur Sigurdsson,Thor Aspelund,Olafur Kjartansson,Elias F. Gudmundsson,Maria K. Jonsdottir,Gudny Eiriksdottir,P.V. Jonsson,Mark A. van Buchem,Vilmundur Gudnason,Lenore J. Launer +9 more
TL;DR: Investigation of the incidence of infarcts in cortical, subcortical, cerebellar, and overall brain regions and how prevalent and incident infarctors associate with cognitive change and incident dementia found men are at greater risk of developing incident brain infarCTs than women.
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Overweight and Obesity in Midlife and Brain Structure and Dementia 26 Years Later The AGES-Reykjavik Study
Emiliano Albanese,Benjamin J. K. Davis,P.V. Jonsson,Milan Chang,Thor Aspelund,Melissa Garcia,Tamara B. Harris,Vilmundur Gudnason,Lenore J. Launer +8 more
TL;DR: Findings do not support the hypothesis that high body mass index in midlife modulates the risk for dementia, and the associations of overweight and obesity at midlife with 1.5-T brain magnetic resonance imaging measures are studied.