P
P W Armstrong
Researcher at St. Michael's Hospital
Publications - 2
Citations - 324
P W Armstrong is an academic researcher from St. Michael's Hospital. The author has contributed to research in topics: In vivo & Endothelium. The author has an hindex of 2, co-authored 2 publications receiving 319 citations.
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Journal ArticleDOI
Extracellular matrix remodeling after balloon angioplasty injury in a rabbit model of restenosis.
Bradley H. Strauss,Robert J. Chisholm,Fred W. Keeley,A I Gotlieb,Richard A. Logan,P W Armstrong +5 more
TL;DR: Significant increases in collagen, elastin, and proteoglycan synthesis, up to 4 to 10 times above control nondamaged contralateral iliac arteries, were noted at 1, 2, and 4 weeks, accompanied by significant increases in synthesis that coincided with the temporal increase in cross-sectional area.
Journal ArticleDOI
Inhibitory role of the coronary arterial endothelium to alpha-adrenergic stimulation in experimental heart failure.
J S Main,C Forster,P W Armstrong +2 more
TL;DR: The data suggest that alpha-adrenergic tone in canine coronary arteries is diminished by pacing-induced CHF because of a decrease in alpha 1-adRenoceptor-mediated constriction and an enhanced capacity of the endothelium to antagonize the direct vascular smooth muscle response of norepinephrine through endothelioceptor-dependent, alpha 2- adreno receptor-mediated relaxations.