P. Wahl

TL;DR: It is demonstrated that incubation of cultured bovine aortic endothelial cells with AGE albumin resulted in the impairment of reduced glutathione and ascorbic acid levels, and supplementation of cellular antioxidative defense mechanisms by extracellularly administered α-lipoic acid reduces AGEalbumin-induced endothelial dysfunction in vitro.

TL;DR: The renal risk is similar in patients with type II and type I diabetes mellitus, and the findings after 25 years were 57% and 46% respectively.

TL;DR: The study shows that leptin serum levels are under control of TNF, a pleiotropic hormone believed to regulate body weight.

TL;DR: Hyperhomocyst(e)inemia is common in nephropathic diabetic patients and may contribute to the enhanced morbidity and mortality from cardiovascular diseases characteristically observed in IDDM patients with diabetic nephrupathy.

TL;DR: An Electrophoretic Mobility Shift Assay based semiquantitative detection system was used to determine NF-kB activation in ex vivo isolated peripheral blood mononuclear cells, which correlated with the degree of albuminuria and with thrombomodulin plasma concentrations, indicative foralbuminuria associated endothelial dysfunction.