P
Pantelis Georgiades
Researcher at The Cyprus Institute
Publications - 15
Citations - 378
Pantelis Georgiades is an academic researcher from The Cyprus Institute. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 9, co-authored 10 publications receiving 293 citations. Previous affiliations of Pantelis Georgiades include Wellcome Trust Centre for Cell-Matrix Research & University of Manchester.
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Particle tracking microrheology of purified gastrointestinal mucins
TL;DR: The rheological characteristics of gastric and duodenal mucin solutions, the building blocks of the mucus layer that covers the epithelia of the two organs, were investigated using particle tracking microrheology to probe the mesoscopic forces that mediate the integrity of the polymer network.
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Reorganisation of the salivary mucin network by dietary components: insights from green tea polyphenols.
Heather S. Davies,Paul D. A. Pudney,Pantelis Georgiades,Thomas A. Waigh,Nigel Hodson,Caroline Ridley,Ewan W. Blanch,David J. Thornton +7 more
TL;DR: It is shown how one dietary compound, the green tea polyphenol epigallocatechin gallate (EGCG), can substantially alter the properties of both the polymeric MUC5B network and monomeric MUC7, contributing to the astringency of green tea.
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Tea Derived Galloylated Polyphenols Cross-Link Purified Gastrointestinal Mucins
TL;DR: It is shown using a combination of particle tracking microrheology and small-angle neutron scattering that polyphenols acts as cross-linkers for purified gastrointestinal mucin, derived from the stomach and the duodenum, with the main active cross-linking component being the galloylated forms of catechins.
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The flexibility and dynamics of the tubules in the endoplasmic reticulum.
Pantelis Georgiades,Victoria J. Allan,Graham D. Wright,Philip G. Woodman,Parinya Udommai,Manloeng A. Chung,Thomas A. Waigh +6 more
TL;DR: The dynamic behaviour of ER tubules in live cells was investigated, and it was found that the ERtubules behaved like semi-flexible fibres under tension.
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A combined small-angle X-ray and neutron scattering study of the structure of purified soluble gastrointestinal mucins.
Pantelis Georgiades,Emanuela Di Cola,Richard K. Heenan,Paul D. A. Pudney,David J. Thornton,Thomas A. Waigh +5 more
TL;DR: The structures of purified soluble porcine gastric and duodenal mucin solutions at neutral and acidic pH were examined using small‐angle X‐ray scattering and neutron scattering experiments, providing evidence for the morphology of the network above the semidilute overlap concentration and above the entanglement concentration.