P
Paola Salvatore
Researcher at University of Naples Federico II
Publications - 152
Citations - 6409
Paola Salvatore is an academic researcher from University of Naples Federico II. The author has contributed to research in topics: Bipolar disorder & Mania. The author has an hindex of 41, co-authored 139 publications receiving 5722 citations. Previous affiliations of Paola Salvatore include United States University & University of Salento.
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Early neonatal death in mice homozygous for a null allele of the insulin receptor gene
Domenico Accili,John Drago,John Drago,Eric J. Lee,Mark D. Johnson,Mark D. Johnson,Martha H. Cool,Paola Salvatore,Laureano D. Asico,Pedro A. Jose,Simeon I. Taylor,Heiner Westphal +11 more
TL;DR: To address the question of whether both metabolic and growth-promoting actions of insulin are mediated by the insulin receptor, mice lacking insulin receptors by targeted mutagenesis in embryo-derived stem (ES) cells are generated.
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The McLean-Harvard first-episode mania study: Prediction of recovery and first recurrence
Mauricio Tohen,Carlos A. Zarate,John Hennen,Hari-Mandir K. Khalsa,Stephen M. Strakowski,Priscilla Gebre-Medhin,Paola Salvatore,Ross J. Baldessarini +7 more
TL;DR: Within 2-4 years of first lifetime hospitalization for mania, all but 2% of patients experienced syndromal recovery, but 28% remained symptomatic, only 43% achieved functional recovery, and 57% switched or had new illness episodes.
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Experimental Phage Therapy against Staphylococcus aureus in Mice
TL;DR: A bacteriophage active against S. aureus, including methicillin-resistant staphylococcal strains, is described, suggesting a potential use of the phage for the control of both local and systemic human S.aureus infections.
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Multiple Versus Single Antipsychotic Agents for Hospitalized Psychiatric Patients: Case-Control Study of Risks Versus Benefits
Franca Centorrino,Jessica L. Gören,John Hennen,Paola Salvatore,James P. Kelleher,Ross J. Baldessarini +5 more
TL;DR: Short-term treatment with multiple antipsychotics was associated with major increases in drug exposure, adverse events, and time in the hospital but with no apparent gain in clinical benefit, requiring further testing in controlled prospective studies.
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Circadian activity rhythm abnormalities in ill and recovered bipolar I disorder patients.
Paola Salvatore,Paola Salvatore,Stefano Ghidini,Gianmaria Zita,Chiara De Panfilis,Samuele Lambertino,Carlo Maggini,Ross J. Baldessarini +7 more
TL;DR: It is suggested that abnormal activity rhythms, including sustained phase advances, may represent enduring (trait) characteristics of BPD patients even during clinical recovery, and may be useful in supporting diagnoses and as an objective phenotype for genetic or other biological studies.