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Paola Zanoli
Researcher at University of Modena and Reggio Emilia
Publications - 62
Citations - 2279
Paola Zanoli is an academic researcher from University of Modena and Reggio Emilia. The author has contributed to research in topics: Ovariectomized rat & Estradiol benzoate. The author has an hindex of 24, co-authored 62 publications receiving 2119 citations.
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Journal ArticleDOI
Pharmacognostic and pharmacological profile of Humulus Lupulus L.
Paola Zanoli,Manuela Zavatti +1 more
TL;DR: The present review describes the morphological, phytochemical and ethnopharmacological aspects of Humulus lupulus L. (Cannabinaceae) and summarizes the most interesting findings obtained in the preclinical and clinical research related to the plant.
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Pharmacological profile of apigenin, a flavonoid isolated from Matricaria chamomilla
TL;DR: The present results seem to suggest that the inhibitory activity of apigenin on locomotor behaviour in rats cannot be ascribed to an interaction with GABA(A)-benzodiazepine receptor but to other neurotransmission systems, since it is not blocked by Ro 15-1788.
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Behavioral characterisation of the flavonoids apigenin and chrysin.
TL;DR: The data demonstrate that in experimental conditions, the two flavonoids were equally able to reduce locomotor activity when injected in rats at a minimal effective dose of 25 mg/kg, however, while chrysin exhibited a clear anxiolytic effect when injected at the dose of 1 mg/ kg, apigenin failed to exert this activity.
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Role of hyperforin in the pharmacological activities of St. John's Wort.
TL;DR: The phloroglucinol derivative hyperforin has been recently shown to be a major antidepressant component in the extract of Hypericum perforatum, and has many other pharmacological effects in vivo and in vitro (antioxidant, anticyclooxygenase-1, and anticarcinogenic effects).
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New insight in the neuropharmacological activity of Humulus lupulus L.
TL;DR: It is shown that Humulus lupulus CO2 extract exerts a pentobarbital sleep-enhancing property without influencing the motor behavior of rats; and an antidepressant activity.