Use of Lawesson's reagent in organic syntheses.

Arylglyoxals in synthesis of heterocyclic compounds.

Interpenetration in extended three-dimensional (3D) arrays has been investigated by a systematic analysis of the crystallographic structural databases, using an ad hoc version of the program package TOPOS. In this paper we describe the comprehensive results of our investigation of interpenetration in organic hydrogen-bonded 3D arrays from the Cambridge Structural Database. The great interest in the self-assembly of organic molecules into hydrogen-bonded supramolecular arrays has prompted us to investigate these systems at a rather unusual level; that is, beyond the formation of synthons, we have examined the topologies of the resulting networks and looked for their entanglements. Within 3D architectures we have extracted a complete list including 122 different motifs showing the phenomenon of interpenetration (76 unseen by the original authors). These organic networks include species assembled by a single or by different building blocks; they are discussed and classified according to the previously introd...

Interpenetrated Three-Dimensional Networks of Hydrogen-Bonded Organic Species: A Systematic Analysis of the Cambridge Structural Database

Data on the synthetic routes to substituted 1,2,3-triazoles, including those containing functional groups, based on cyclisation of various nitrogen compounds published during the last 15 years are described. Examples of using new triazole derivatives in agrochemistry, medicine and engineering are given.

https://iopscience.iop.org/article/10.1070/RC2005v074n04ABEH000893/pdf

1,2,3-Triazole and its derivatives. Development of methods for the formation of the triazole ring

Corticotropin-releasing factor (CRF) antagonists have formula (I), wherein A, R3, R4 and R5 are as defined herein. They are useful in the treatment of illnesses induced or facilitated by CRF, such as inflammatory disorders, and depression and anxiety related disorders.

Pyrazolopyrimidines as crf antagonists

A synthetic entry to isoxazolo[5,4‐d]pyrimidine‐4(5H)thione and isothiazolo[4,3‐d]isoxazole

Trente 6-trifluoromethylpyrazolo [3,4-d] pyrimidines ont ete synthetisees et testees pour leur activite antifongique in vitro contre dix champignons phytopathogenes de differentes classes taxonomiques. Six de ces composes ont une action remarquable contre Sclerotinia minor, Corticium solani et Phoma betae. On discute des relations structure-activite sur la base de ces resultats et des etudes anterieures

Synthesis and in-vitro antifungal activity of 6-trifluoromethylpyrazolo[3,4-d]pyrimidines

Synthesis of 6-substituted imidazo 4,5-c pyrazole-5-thiones

A new general and efficient synthesis of imidazo[4,5-c]pyrazole derivatives

Douze 6-trifluoromethylpyrazolo [3,4-d] pyrimidine-4(5H)-thiones ont ete synthetisees. On les a testees in vitro pour leur activite fongicide contre une serie de champignons phytopathogenes de differentes classes taxonomiques. Les valeurs EC50 (50% d'inhibition de croissance) et MIC (concentration minimale qui inhibe totalement la croissance) de quatre composes sont comparables ou inferieures a celles de fongicides commerciaux de reference qui controlent Sclerotinia minor, Corticium solani et Pythium ultimum

Paolo Giori

Papers

A synthetic entry to isoxazolo[5,4‐d]pyrimidine‐4(5H)thione and isothiazolo[4,3‐d]isoxazole

Synthesis and in-vitro antifungal activity of 6-trifluoromethylpyrazolo[3,4-d]pyrimidines

Synthesis of 6-substituted imidazo 4,5-c pyrazole-5-thiones

A new general and efficient synthesis of imidazo[4,5-c]pyrazole derivatives

Synthesis and in‐vitro antifungal activity of 6‐trifluoromethyipyrazolo[3,4‐6d]pyrimidin‐4(5H)‐thiones