Journal ArticleDOI
A new general and efficient synthesis of imidazo[4,5-c]pyrazole derivatives
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TLDR
In this article, a new general and efficient synthesis of imidazo[4,5-c]pyrazoles (5 ) was reported, and the key step of this synthetic procedure is the intramolecular cyclodehydration of 5 -alkylamino-4 -nitrosopyrazoles, which affords the title compounds in good yields.About:
This article is published in Tetrahedron.The article was published on 1990-01-01. It has received 15 citations till now. The article focuses on the topics: Intramolecular reaction & Pyrazole.read more
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Solid phase polyamine linkers-their utility in synthesis and the preparation of directed libraries against trypanothione reductase
TL;DR: In this article, a variety of diprotected polymines are anchored to a solid support and used in solid phase chemistry and library generation, and they are shown to be useful in a wide range of applications.
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Synthesis of 4-(pyrazol-5-yl)-1,2,4-triazole-3-thiones
TL;DR: Condensation of pyrazolyl isothiocyanates 2 with N-substituted hydrazines provided the 2-methyl/phenyl-4-(pyrazol-5-yl)thiosemicarbazides 3.
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Synthetic methods for polyamine linkers and their application to combinatorial chemistry
TL;DR: Methods for the solid-phase immobilisation of polyamines for use in synthetic and combinatorial chemistry are presented and how they have been employed in the preparation of a number of important polyamine conjugates and polyamine libraries are described.
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Studies on the Synthesis and Cyclization Reactions of2-(5-Amino-3-arylpyrazol-1-yl)-3-methylquinoxalines
TL;DR: A series of 2-(5-amino-3-arylpyrazol-1-yl)-3-methylquinoxalines (2a-d) has been synthesized by the condensation of 2-hydrazino- 3-methyl-quinoxaline (1) with substitutedbenzoylacetonitriles and converted into the corresponding 3,4-diaryl-1-(3-miquoxalin-2-yl)4,8-dihydro-1H======¯¯¯¯-pyrazolo[3,4
References
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Journal ArticleDOI
Purine, XII: Über die Cyclisierung von 4‐Alkylamino‐5‐nitrosouracilen und die Synthese von 8‐substituierten Xanthinen und Bis(theophyllin‐8‐yl)‐alkan‐Derivaten
TL;DR: In this paper, the cyclisierung of 4-Alkylamino-5-nitrosouracils is investigated by means of a differential thermogravimetric method.
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Synthesis and in-vitro antifungal activity of 6-trifluoromethylpyrazolo[3,4-d]pyrimidines
T. Poli,Chiara Beatrice Vicentini,Vincenzo Brandolini,Augusto C. Veronese,Maurizio Manfrini,Mario Guarneri,Paolo Giori +6 more
TL;DR: Trente 6-trifluoromethylpyrazolo [3,4-d] pyrimidines ont ete synthetisees et testees pour leur activite antifongique in vitro contre dix champignons phytopathogenes de differentes classes taxonomiques as discussed by the authors.
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Syntheses of 2‐arylimidazole derivatives through annelations employing benzylamines
TL;DR: Annelations of benzylamines with hydroximino derivatives of pentane-2,4-dione or of alkyl acetoacetates, alkacetoacetamides, and acetobensilides, afford imidazole derivatives as discussed by the authors.
Journal ArticleDOI
Synthesis and in‐vitro antifungal activity of 6‐trifluoromethyipyrazolo[3,4‐6d]pyrimidin‐4(5H)‐thiones
Chiara Beatrice Vicentini,T. Poli,Augusto C. Veronese,Vincenzo Brandolini,Maurizio Manfrini,Mario Guarneri,Paolo Giori +6 more
TL;DR: Douze 6-trifluoromethylpyrazolo [3,4-d] pyrimidine-4(5H)-thiones ont ete synthetisees as mentioned in this paper.
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Synthesen stickstoffhaltiger Heterocyclen, XVIII. Über ortho-Kondensationen heterocyclischer o-Amino-carbonsäure-Derivate
Alfred Dornow,Ehrhard Hinz +1 more
TL;DR: In this article, 4-Amino-pyridin-carbonsaure-(5)-esters mit Estern aliphatischer carbonsauren wurden einige Dihydroxy pyridino-pyrimidine dargestellt, deren Bildung durch Reaktion der intermediar entstehenden Isocyanate mit der benachbarten NH2-Gruppe ist.