P
Parkson Lee-Gau Chong
Researcher at Temple University
Publications - 95
Citations - 3341
Parkson Lee-Gau Chong is an academic researcher from Temple University. The author has contributed to research in topics: Membrane & Sterol. The author has an hindex of 33, co-authored 93 publications receiving 3146 citations. Previous affiliations of Parkson Lee-Gau Chong include Meharry Medical College & Icahn School of Medicine at Mount Sinai.
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Journal ArticleDOI
Targeting VEGF-encapsulated immunoliposomes to MI heart improves vascularity and cardiac function
Robert C. Scott,Jenna M. Rosano,Zhanna Ivanov,Bin Wang,Parkson Lee-Gau Chong,Andrew C. Issekutz,Deborah L. Crabbe,Mohammad F. Kiani +7 more
TL;DR: The technology to enhance the morphology and function of postinfarct neovasculature is developed and targeted delivery of low doses of proangiogenic compounds to post‐MI tissue results in significant improvements in cardiac function and vascular structure.
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Mechanisms of inhibition of (Na,K)-ATPase by hydrostatic pressure studied with fluorescent probes.
TL;DR: It is concluded that increased pressure decreases the membrane fluidity which hinders conformational transitions associated with rate-limiting steps of the (Na,K)-ATPase reaction, and it is proposed that ion-bound or -occluded forms of ( Na,K) ATPase are stabilized by pressure because they occupy a smaller volume.
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Molecular modeling of archaebacterial bipolar tetraether lipid membranes
TL;DR: The biological implication of this study is that the cyclopentane ring could increase GDNT membrane thermal stability, which explains why the number of cyclopENTane rings in archaebacterial lipid increases with increasing growth temperature.
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Evidence for regular distribution of sterols in liquid crystalline phosphatidylcholine bilayers.
TL;DR: The fluorescence dips provide compelling evidence that a naturally occurring sterol is regularly distributed at fixed compositional fractions, consistent with the presence of hexagonal super-lattices in the fluid membranes.
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Effects of hydrostatic pressure on the location of PRODAN in lipid bilayers and cellular membranes
TL;DR: The effects of hydrostatic pressure on the location of 6-propionyl-2-(dimethylamino)naphthalene (PRODAN), an environmentally sensitive fluorescent probe, in phosphatidylcholine lipid bilayers and in goldfish brain synaptic membranes have been studied by fluorescence spectroscopy over the pressure range of 0.001-2 kbar.