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Patience O. Obi

Researcher at University of Manitoba

Publications -  11
Citations -  456

Patience O. Obi is an academic researcher from University of Manitoba. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 2, co-authored 5 publications receiving 75 citations. Previous affiliations of Patience O. Obi include Boston Children's Hospital.

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A Review of Exosomal Isolation Methods: Is Size Exclusion Chromatography the Best Option?

TL;DR: It is argued that exosomes isolated via SEC are relatively pure and functional, and that this methodology is reproducible, scalable, inexpensive, and does not require specialized equipment or user expertise.
Posted ContentDOI

A Review of Exosomal Isolation Methods: Is Size Exclusion Chromatography the Best Option?

TL;DR: It is argued that exosomes isolated via SEC are relatively pure and functional, and that this methodology is reproducible, scalable, inexpensive, and does not require specialized equipment or user expertise.
Journal ArticleDOI

Exosomes, autophagy and ER stress pathways in human diseases: Cross-regulation and therapeutic approaches.

TL;DR: In this paper , the authors review the available information on the mechanisms that control autophagy, ER stress and EV pathways, with the view that a better understanding of their crosstalk and balance may improve our knowledge on the pathogenesis and treatment of human diseases, where these pathways are dysregulated.
Journal ArticleDOI

Characterizing Extracellular Vesicles and Particles Derived from Skeletal Muscle Myoblasts and Myotubes and the Effect of Acute Contractile Activity

TL;DR: The data show that EVs differed in size, distribution, protein yield and expression of subtype markers pre vs. post skeletal muscle–differentiation into myotubes, and there was no effect of acute stimulation on biophysical profile or protein markers in EPs.
Posted ContentDOI

Extracellular vesicles as predictors of individual response to exercise training in youth living with obesity

TL;DR: The data suggest that youth with obesity that respond to exercise training produce larger EVs, with lower exosome- and higher microvesicle-specific protein expression, and the individual response to exercise has yet to be fully elucidated.