Patricia Griffith

TL;DR: The early use of deferoxamine in an amount proportional to the transfusional iron load reduces the body iron burden and helps protect against diabetes mellitus, cardiac disease, and early death in patients with thalassemia major.

TL;DR: Variability resulting from factors other than iron status limits the clinical usefulness of the plasma ferritin concentration as a predictor of body iron stores, according to the 95% prediction intervals for hepatic iron concentration.

TL;DR: Patients with pancytopenia and cellular bone marrow showed response rates similar to those of patients with chronic or moderate aplastic anemia, and patients with a variety of bone marrow failure syndromes continued to show improvement to 1 year posttreatment.

TL;DR: In this article, the authors used radionuclide cineangiography to determine left ventricular ejection fraction during exercise in 24 patients with transfusion-dependent, congenital anemias, 21 of whom had severe beta thalassemia.

TL;DR: A combination of cyclosporine and corticosteroids may be effective therapy in patients with aplastic anaemia who have failed ATG treatment, andOccasional cases of congenital and acquired pure red cell aplasia may also respond to cyclospora.