Patricia Klotz

TL;DR: To determine the effectiveness of early, routine antioxidant supplementation using α-tocopherol and ascorbic acid in reducing the rate of pulmonary morbidity and organ dysfunction in critically ill surgical patients.

TL;DR: It is found that epidural analgesia is associated with a decrease in the rate of nosocomial pneumonia and a shorter duration of mechanical ventilation after rib fractures, which is limited in the trauma population due to numerous exclusion criteria.

TL;DR: Among patients with moderate to severe TBI, out-of-hospital tranexamic acid administration within 2 hours of injury compared with placebo did not significantly improve 6-month neurologic outcome as measured by the Glasgow Outcome Scale-Extended.

TL;DR: Children hospitalized for an extremity fracture suffered dramatic declines in physical and psychosocial well-being during the first 3 months postinjury; by 1 year postin injury, most children recovered; however, children with a tibia and/or fibula fracture still reported significantly poorer physical functioning.

TL;DR: Ventilator-dependent surgical patients receiving oxandrolone had a more prolonged course of mechanical ventilation, suggesting that ox androlone may be detrimental in this circumstance.