Patricia Rawsthorne

TL;DR: The associations of immune mediated diseases in extraintestinal sites may help to further the understanding of IBD pathogenesis, and it may help in developing a paradigm of disease subsets.

TL;DR: The authors have successfully established and validated a population-based database of inflammatory bowel disease based on administrative data and indicate the presence of important environmental risk factors, which warrants further investigation.

TL;DR: Comparing IBD respondents with and without lifetime anxiety or mood disorder, those with a disorder reported lower quality of life and earlier onset of IBD symptoms and there was a trend toward earlier IBD diagnosis.

TL;DR: This study reinforced the increased risk associated with family history, being Jewish, and smoking history, however, a number of significant associations with CD and UC on univariate and multivariate analysis may support the “hygiene hypothesis” and warrant further exploration in prospective studies.

TL;DR: Multivariate regression showed that those with active IBD had higher levels of distress, health anxiety, and perceived stress, lower social support, well-being and mastery, and poorer disease-specific QOL, relative to those with inactive disease.