Showing papers in "Clinical Gastroenterology and Hepatology in 2006"

TL;DR: D diagnosis of autoimmune pancreatitis can be made in patients with > or =1 of these criteria: diagnostic histology, characteristic imaging on computed tomography and pancreatography with elevated serum IgG4 level, or response to steroid therapy of pancreatic/extrapancreatic manifestations of AIP.

TL;DR: Although the unadjusted analysis showed an increased risk for infection with infliximab use, multivariate logistic regression analysis suggested that inflIXimab was not an independent predictor of serious infections.

TL;DR: Diabetes is associated with an increased risk for HCC, however, more research is required to examine issues related to the duration and treatment of diabetes, and confounding by diet and obesity.

TL;DR: Here it is shown that the use of genetically modified bacteria for mucosal delivery of proteins is a feasible strategy in human beings and is suitable as maintenance treatment for chronic intestinal disease.

TL;DR: SFED treatment was associated with clinical and histologic improvement in EE in an observational study and should be considered as an option in the initial management of children with EE.

TL;DR: For Crohn's disease patients treated with scheduled maintenance infusions of inflIXimab, the trough serum concentration of infliximab predicts clinical outcome.

TL;DR: Curcumin seems to be a promising and safe medication for maintaining remission in patients with quiescent UC, and improved both CAI and EI, thus suppressing the morbidity associated with UC.

TL;DR: Screening EUS and CT diagnosed significant asymptomatic pancreatic and extrapancreatic neoplasms in high-risk individuals and IPMN should be considered a part of the phenotype of familial pancreatic cancer.

TL;DR: A group of experts on the subject was convened to develop the following new definitions: "Intestinal failure results from obstruction, dysmotility, surgical resection, congenital defect, or disease-associated loss of absorption and is characterized by the inability to maintain protein-energy, fluid, electrolyte, or micronutrient balance."

TL;DR: In this paper, a confocal laser endomicroscopy of Barrett's esophagus was used to detect cellular and vascular changes in Barrett's epithelium at high resolution during ongoing endoscopy in 63 patients.

TL;DR: A treatment algorithm for CHB previously developed and published by a panel of United States hepatologists was revised based on new developments in the understanding of CHB, the availability of more sensitive molecular diagnostic testing, the addition of new treatments, and better understanding of the advantages and disadvantages of approved therapies.

TL;DR: In children with active and recently diagnosed CD, a short course of polymeric diet is more effective than corticosteroids in inducing healing of gut inflammatory lesions.

TL;DR: The combination of curcumin and quercetin appears to reduce the number and size of ileal and rectal adenomas in patients with FAP without appreciable toxicity.

TL;DR: Preliminary results from this trial define the prevalence and incidence of dysplasia and cancer in a multicenter cohort of patients with Barrett's esophagus and evaluate the paths of progression in a large multicenter cohorts of BE patients.

TL;DR: This review analyzes currently available literature and describes the clinical characteristics of Peutz-Jeghers syndrome, assesses the risk of malignancy in this disorder, and delineates management and surveillance recommendations for affected individuals.

TL;DR: The survival of cirrhotic patients with first episode of ascite is relatively high, and it is mainly influenced by age and Child-Pugh score at the time of ascites decompensation, as well as by DH development.

TL;DR: The ESD is applicable to the esophagus with promising results, but notification of risk is essential.

TL;DR: Incomplete polypectomy might play an important role in the development of interval colorectal cancer and no association between other colonoscopy-related factors or tumor characteristics and interval cancers was found.

TL;DR: An OCT image scoring system based on histopathologic characteristics has the potential to identify IMC and HGD in Barrett's esophagus.

TL;DR: Two years of treatment with UDCA in combination with vitamin E improved laboratory values and hepatic steatosis of patients with NASH and larger trials are warranted.

TL;DR: Orlistat improves serum ALT levels and steatosis on US in NAFLD patients, beyond its effect on weight reduction.

TL;DR: CSA is an effective short- to medium-term treatment for patients with severe UC but at 7 years, 88% of patients will require a colectomy, and azathioprine-naive patients have better outcomes.

TL;DR: Short- and long-term success is similar for graded PD and laparoscopic HM, and Achalasia patients need careful long- term follow-up evaluation.

TL;DR: Multivariate regression showed that those with active IBD had higher levels of distress, health anxiety, and perceived stress, lower social support, well-being and mastery, and poorer disease-specific QOL, relative to those with inactive disease.

TL;DR: Clinically significant infliximab levels were detected in the offspring and the timing of infusions to minimize antibody transfer to the fetus might be an important strategic consideration when therapeutic antibodies are used in pregnancy.

TL;DR: Adenomas 5-10 mm in size harbor pathologically significant histology, and the need for removal of these lesions must be addressed to optimize colorectal cancer prevention.

TL;DR: NSAID ingestion is associated with frequent and early clinical relapse of quiescent inflammatory bowel disease, and the mechanism appears to be due to dual inhibition of the COX enzymes.

TL;DR: Longitudinal risk of malignant transformation of IPMT since the first sign is time-dependent, and patients with BD IPMT present a much lower risk, justifying a nonoperative surveillance.

TL;DR: A systematic literature review of the published literature comparing EUS and CT for preoperative assessment of pancreatic cancer concluded that the sensitivity of EUS was superior to CT.

TL;DR: Therapy with celecoxib for up to 14 days did not have a greater relapse rate than placebo in patients with ulcerative colitis in remission who had a present or past history of nonspecific arthritis, arthralgia, or other condition amenable to nonsteroidal anti-inflammatory drug therapy.