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Showing papers by "Patrizia Brigidi published in 1988"


Journal ArticleDOI
TL;DR: Dl-Ethionine-resistant mutants of Saccharomyces uvarum ATCC 26602 were found to overproduce exogenous l-methionine and these fusants were stable after ten passages on complete medium.
Abstract: dl-Ethionine-resistant mutants of Saccharomyces uvarum ATCC 26602 were found to overproduce exogenous l-methionine. dl-Ethionine-resistant mutant ER 108, carrying a mutation to chloramphenicol resistance was converted to petite form, and protoplasts obtained from it were fused with protoplasts from antibiotic-sensitive S. cerevisiae X2928 carrying six auxotrophies. The resulting fusants maintained four auxotrophies and were capable of overproducing l-methionine. These fusants were stable after ten passages on complete medium.

23 citations


Journal ArticleDOI
TL;DR: Circular dichroism shows that small segments of right-handed B-DNA in solution interact together to give a left-handed cholesteric superhelix.
Abstract: Circular dichroism shows that small segments of right-handed B-DNA in solution interact together to give a left-handed cholesteric superhelix.

16 citations


Journal Article
TL;DR: A short series of N-monosubstituted (aryl, aminoacyl, dipeptidyl)-2-(2-aminothiazol-4-yl)-(Z) -2-methoxyiminoacetamides showed a somewhat interesting inhibitory action against Cryptococcus neoformans.
Abstract: A short series of N-monosubstituted (aryl, aminoacyl, dipeptidyl)-2-(2-aminothiazol-4-yl)-(Z) -2-methoxyiminoacetamides was synthesized and tested for antimicrobial activity. A few members showed a somewhat interesting inhibitory action against Cryptococcus neoformans (MIC = 150 micrograms/ml).

2 citations