Showing papers by "Paul Doty published in 1960"
TL;DR: A chronology of key events and publications leading up to and including the publication of the first book on Heredity, edited by P. Doty and J. Marmur and published in 1960.
Abstract: 1 Doty, P., J. Marmur, J. Eigner, and C. Schildkraut, these PROCEEDINGS, 46, 461 (1960). 2 Rice, S. A., and P. Doty, J. Am. Chem. Soc., 79, 3937 (1957). 3Doty, P., H. Boedtker, J. R. Fresco, R. Haselkorn, and M. Litt, these PROCEEDINGS, 45, 482 (1959). 4 Marmur, J., and P. Doty, Nature, 183, 1427 (1959). 5 Doty, P., J. Marmur, and N. Sueoka, in Brookhaven Symposia in Biology, 12, 1 (1959). 6 Meselson, M., and F. Stahl, these PROCEEDINGS, 44, 671 (1958). 7 Zamenhof, S., H. E. Alexander, and G. Leidy, J. Exptl. Med., 98, 373 (1953); Zamehhof, S., in The Chenmical Basis of Heredity (Baltimore: Johns Hopkins Press, 1957), p. 373. 8 Roger, M., and R. D. Hotchkiss (personal communication). 9 Fox, M. S., and R. D. Hotchkiss, Nature, 179, 1322 (1957). 10 Litt, M., J. Marmur, H. Ephrussi-Taylor, and P. Doty, these PROCEEDINGS, 44, 144 (1958). 11 Hotchkiss, R. D., and A. Evans, Cold Spring Harbor Symp. Quant. Biol., 23, 85 (1958). 12 Marmur, J. (in preparation.) 13 Lerman, L. S., and L. J. Tolmach, Biochim. Biophys. Acta, 33, 371 (1959). 14 Pratt, D., and G. S. Stent, these PROCEEDINGS, 45, 1507 (1959). 15 Tessman, I., Virology, 9, 375 (1959). 16 Sinsheimer, R. L., J. Mol. Biol., 1, 45 (1959). 17 Bracco, R. M., M. R. Krauss, A. S. Roe, and C. M. MacLeod, J. Exptl. Med., 106, 247 (1957). 18 Fox, M. S., Biochem. Biophys. Acta, 26, 83 (1957); Lerman, L .S., and L. J. Tolmach, Biochim. Biophys. Acta, 26, 68 (1957). 19 Goodgal, S. H., and R. M. Herriott, in The Chemical Basis of Heredity (Baltimore: Johns Hopkins Press, 1957), p. 336. 20 Schaeffer, P., Symp. Soc. Exptl. Biol., 12, 60 (1958).
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226 citations
TL;DR: In this article, the authors report the optical rotatory properties of poly-L-tyrosine in dilute solutions in pyridine, in dimethyl formamide, and in aqueous alkali.
Abstract: IN a recent communication1, Downie, Elliott and Hanby report that the optical rotatory dispersion of poly-L-tyrosine is unusual and, as a result, its configuration cannot be assigned by analogy with polypeptides having normal dispersion characteristics. However, they interpret their data, together with unspecified infra-red spectral and X-ray diffraction observations of films, as indicating that “it is more probable that in dilute solutions in pyridine, in dimethyl formamide, and in aqueous alkali, poly-L-tyrosine is in a random coil configuration”. Our study of this problem has led to somewhat different conclusions: that the configuration in pyridine and dimethyl formamide is that of the α-helix, whereas in alkaline solution the configuration is dependent on pH, indicative of the random-coil configuration. The basis of the configurational assignments will be published elsewhere in detail, but we wish to summarize them here and report the optical rotatory characteristics of the two forms.
24 citations
TL;DR: A linear polypeptide of L -glutamic acid, l -lysine and l -tyrosine has been synthesised and found to behave as a strong antigen giving precipitin, agar diffusion and ring tests comparable to typical proteins.
22 citations