Paul Forsythe

TL;DR: Chronic treatment with L. rhamnosus induced region-dependent alterations in GABAB1b mRNA in the brain with increases in cortical regions and concomitant reductions in expression in the hippocampus, amygdala, and locus coeruleus, in comparison with control-fed mice, highlighting the important role of bacteria in the bidirectional communication of the gut–brain axis.

TL;DR: Understanding the induction and transmission of signals in the vagus nerve may have important implications for the development of microbial-or nutrition based therapeutic strategies for mood disorders.

TL;DR: There are rapidly coalescing clusters of evidence which point to the possibility that variations in the composition of gut microbes may be associated with changes in the normal functioning of the nervous system, and the concept should be explored further to increase the understanding of mood disorders, and possibly even uncover missing links to a number of co-morbid medical diseases.

TL;DR: A role for nonantigen-specific CD4(+)CD25(+)Foxp3(+) regulatory T cells in attenuating the allergic airway response following oral treatment with L. reuteri is found and may have therapeutic potential in controlling the Th2 bias observed in atopic individuals.

TL;DR: It is established that RANTES is a chemotactic and activating factor for eosinophils, unlike IL-3, who did not affect the survival of eos in a 4-day culture system.