P
Paul Soler
Researcher at French Institute of Health and Medical Research
Publications - 65
Citations - 5489
Paul Soler is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Lung & Bronchoalveolar lavage. The author has an hindex of 35, co-authored 65 publications receiving 5297 citations. Previous affiliations of Paul Soler include University of Paris & Paris Diderot University.
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Journal ArticleDOI
High Inflation Pressure Pulmonary Edema: Respective Effects of High Airway Pressure, High Tidal Volume, and Positive End-expiratory Pressure
TL;DR: To the authors' knowledge, this constitutes the first example of a protective effect of PEEP during permeability edema, which was markedly reduced by PEEP and preserved the normal ultrastructural aspect of the alveolar epithelium.
Journal ArticleDOI
Diagnosis of nosocomial bacterial pneumonia in intubated patients undergoing ventilation: comparison of the usefulness of bronchoalveolar lavage and the protected specimen brush.
Jean Chastre,Jean-Yves Fagon,Paul Soler,Marylin Bornet,Y. Domart,Jean-Louis Trouillet,Claude Gibert,Allan J. Hange +7 more
TL;DR: The protected specimen brush and microscopic identification of intracellular organisms in cells recovered by lavage yield useful and complementary information, and together permit rapid and specific treatment of most patients with nosocomial pneumonia.
Journal ArticleDOI
Analysis of vancomycin entry into pulmonary lining fluid by bronchoalveolar lavage in critically ill patients.
C. Lamer,V de Beco,Paul Soler,S Calvat,J. Y. Fagon,Marie Christine Dombret,R Farinotti,Jean Chastre,C Gibert +8 more
TL;DR: The results suggest that the vancomycin distribution includes the ELF of the lower respiratory tract at a concentration that is dependent upon the levels in blood and the alveolar capillary membrane protein permeability.
Journal ArticleDOI
Mechanical ventilation-induced pulmonary edema : interaction with previous lung alterations
TL;DR: HV45 after ANTU produced significantly greater increases in Qwl, DLW, and ASp than expected from the sum of the effects of either insult alone, indicating synergistic adverse effects on pulmonary edema.
Journal Article
Cytokine patterns in tuberculous and sarcoid granulomas: correlations with histopathologic features of the granulomatous response.
Anne Bergeron,Marcel Bonay,M Kambouchner,Denise Lecossier,M. Riquet,Paul Soler,Allan J. Hance,Abdellatif Tazi +7 more
TL;DR: It is demonstrated that the formation of tuberculous and sarcoid granulomas in humans is associated with the expression of characteristic cytokine profiles and indicated that theexpression of certain cytokines is associatedWith the development of specific pathologic features in the resultinggranulomas.