Head direction cells and the neurophysiological basis for a sense of direction.

The thalamocortical vestibular system in animals and humans

The origins of cerebral lateralization in humans are traced to the asymmetric prenatal development of the ear and labyrinth. Aural lateralization is hypothesized to result from an asymmetry in craniofacial development, whereas vestibular dominance is traced to the position of the fetus during the final trimester. A right-ear sensitivity advantage may contribute to a left-hemispheric advantage in speech perception and language functions, whereas left-otolithic dominance may independently promote right-sided motoric dominance and a right-hemispheric superiority in most visuospatial functions. The emergence of handedness is linked to the assumption of an upright posture in the early hominids, whereas the failure to develop clear vestibular asymmetry may underlie the poor motoric lateralization found in several neurodevelopmental disorders.

A general theory concerning the prenatal origins of cerebral lateralization in humans.

Antagonism of cortical excitation of striatal neurons by glutamic acid diethyl ester: evidence for glutamic acid as an excitatory transmitter in the rat striatum.

A great number of earlier reported experimental data dealing with the role of dopamine in dopamine-loaded structures within the mammalian brain have raised questions concerning the concept of dopamine as an inhibitory agent acting on one type of receptor. A critical review of the anatomical, histochemical, electrophysiological, pharmacological and functional studies reveals that the dopamine-loaded structures are marked by an internal differentiation at various levels. It is attempted to demonstrate that this is due to a heterogeneous distribution of two distinct types of dopamine-receptors, each characterized by their own properties: DAe- and DAi-receptors. Furthermore, the experimental and clinical. implications are discussed in view of the hypothesis that balance between both types of receptors is essential for normal psychomotor functioning.

Excitation-mediating and inhibition-mediating dopamine-receptors: a new concept towards a better understanding of electrophysiological, biochemical, pharmacological, functional and clinical data.

Vestibular input to the caudate nucleus

Brain stem pathways for vestibular projections to cerebral cortex in the cat.

Intrinsic connections of caudate neurons. I. Locally evoked field potentials and extracellular unitary activity.

Intrinsic connections of caudate neurons. Locally evoked intracellular responses.

Technique for vestibular neurotomy in the rat.

Paula B. Copack

Papers

Vestibular input to the caudate nucleus

Brain stem pathways for vestibular projections to cerebral cortex in the cat.

Intrinsic connections of caudate neurons. I. Locally evoked field potentials and extracellular unitary activity.

Intrinsic connections of caudate neurons. Locally evoked intracellular responses.

Technique for vestibular neurotomy in the rat.