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Paula Reventun
Researcher at University of Alcalá
Publications - 15
Citations - 252
Paula Reventun is an academic researcher from University of Alcalá. The author has contributed to research in topics: Medicine & Enos. The author has an hindex of 6, co-authored 10 publications receiving 147 citations. Previous affiliations of Paula Reventun include Johns Hopkins University & Universidad Francisco de Vitoria.
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Journal ArticleDOI
Oral administration of bisphenol A induces high blood pressure through angiotensin II/CaMKII-dependent uncoupling of eNOS
Marta Saura,Susana Marquez,Paula Reventun,Nuria Olea-Herrero,María I. Arenas,Rafael Moreno-Gómez-Toledano,Mónica Gómez-Parrizas,Carmen Muñoz-Moreno,Marta González-Santander,Carlos Zaragoza,Ricardo J. Bosch +10 more
TL;DR: Oral administration of bisphenol A induces high blood pressure through angiotensin II/CaMKII‐dependent uncoupling of eNOS, which suggests that AngII uncouples eN OS and contributes to the BPA‐induced endothelial dysfunction by promoting oxidative and nitrosative stress.
Journal ArticleDOI
Bisphenol A induces coronary endothelial cell necroptosis by activating RIP3/CamKII dependent pathway.
Paula Reventun,Sandra Sánchez-Esteban,Alberto Cook,Irene Cuadrado,Carolina Roza,Rafael Moreno-Gómez-Toledano,Carmen Muñoz,Carlos Zaragoza,Ricardo J. Bosch,Marta Saura +9 more
TL;DR: The results reveal a novel pathogenic role of BPA on the coronary circulation and induces endothelial cell necroptosis, promotes the weakening of coronary vascular wall, which caused internal ventricular hemorrhages, delaying the reparative process and ultimately leading to cardiac dysfunction.
Journal ArticleDOI
EMMPRIN-Targeted Magnetic Nanoparticles for In Vivo Visualization and Regression of Acute Myocardial Infarction.
Irene Cuadrado,María José G.M. Piedras,Irene Herruzo,María del Carmen Turpin,Borja Castejón,Paula Reventun,Ana M. Martin,Marta Saura,J.L. Zamorano,Carlos Zaragoza +9 more
TL;DR: Injection of NAP9 at the time of or one day after IR, was enough to reduce progression of myocardial cell death when compared to Control and NAPSC injected mice and EMMPRIN targeted nanoparticles as a new approach to the mitigation of ischemic/reperfusion injury.
Journal ArticleDOI
iNOS-Derived Nitric Oxide Induces Integrin-Linked Kinase Endocytic Lysosome-Mediated Degradation in the Vascular Endothelium
Paula Reventun,Matilde Alique,Irene Cuadrado,Susana Marquez,Rocío Toro,Carlos Zaragoza,Marta Saura +6 more
TL;DR: Endocytosis regulates ILK signaling in vascular remodeling where there is an overload of inducible NO, and thus its inhibition may represent a novel target to fight atherosclerotic disease.
Journal ArticleDOI
Bisphenol A impaired cell adhesion by altering the expression of adhesion and cytoskeleton proteins on human podocytes.
Rafael Moreno-Gómez-Toledano,María I. Arenas,Clara González-Martínez,Nuria Olea-Herrero,Paula Reventun,Michele Di Nunzio,Sandra Sánchez-Esteban,Eduardo Arilla-Ferreiro,Marta Saura,Ricardo J. Bosch +9 more
TL;DR: Data show that BPA induced a novel type of podocytopathy characterizes by an impairment of podocyte adhesion, by altering the expression of adhesion and cytoskeleton proteins, which provide a mechanism by which BPA could participate in the pathogenesis and progression of renal diseases.