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Pedro Ismael da Silva

Researcher at Instituto Butantan

Publications -  36
Citations -  988

Pedro Ismael da Silva is an academic researcher from Instituto Butantan. The author has contributed to research in topics: Antimicrobial peptides & Antimicrobial. The author has an hindex of 16, co-authored 34 publications receiving 837 citations. Previous affiliations of Pedro Ismael da Silva include University of São Paulo.

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Antimicrobial activity of a bovine hemoglobin fragment in the tick Boophilus microplus.

TL;DR: The antibacterial activity detected in tick gut contents is the result of enzymatic processing of a host protein, hemoglobin, which may be used by ticks as a defense against microorganisms.
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Acanthoscurrin: a novel glycine-rich antimicrobial peptide constitutively expressed in the hemocytes of the spider Acanthoscurria gomesiana.

TL;DR: A combination of Edman degradation, mass spectrometry and cDNA cloning revealed the presence of two isoforms of acanthoscurrin, differing by two glycine residues, which have no structural similarities with already known glycine-rich antimicrobial peptides from animals and plants.
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Unraveling the antifungal activity of a South American rattlesnake toxin crotamine

TL;DR: Results suggest that, at low concentration, crotamine is a potentially valuable anti-yeast or candicidal agent, with low harmful effects on normal mammal cells, justifying further studies on its mechanisms of action aiming medical and industrial applications.
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Rondonin an antifungal peptide from spider (Acanthoscurria rondoniae) haemolymph.

TL;DR: It is concluded that the antifungal activity detected in the plasma of these spiders is the result of enzymatic processing of a protein that delivers oxygen in the haemolymph of many chelicerate.
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Antimicrobial compounds from natural sources

TL;DR: Several scientific studies mainly focused on natural products with antimicrobial activity are presented, which are the case of the natural antimicrobial peptides (AMPs) and host defense peptide (HDPs) and this topic also includes recent studies on the roles of honey hydrogen peroxide in antimacterial activity against resistant microbial strains, as well as the use of essential oils for food preservation.