P
Peter A. Akah
Researcher at University of Nigeria, Nsukka
Publications - 169
Citations - 3764
Peter A. Akah is an academic researcher from University of Nigeria, Nsukka. The author has contributed to research in topics: Alloxan & Acute toxicity. The author has an hindex of 33, co-authored 164 publications receiving 3422 citations. Previous affiliations of Peter A. Akah include Nnamdi Azikiwe University & Novena University.
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Journal ArticleDOI
Behavioural effect of Pavetta crassipes extract on rodents.
Samson Amos,Peter A. Akah,Nkechi M. Enwerem,B. A. Chindo,Isa M. Hussaini,Charles Wambebe,Karniyus S. Gamaniel +6 more
TL;DR: The results suggest that the extract of P. crassipes contains biologically active substance(s) that might be acting centrally through the inhibition of dopaminergic pathway or a system linked to this pathway to mediate the observed pharmacological effects.
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Extracts of Ficus exasperata leaf inhibit topical and systemic inflammation in rodents and suppress LPS-induced expression of mediators of inflammation in macrophages.
TL;DR: Results show that F. exasperata leaf extracts possess anti-inflammatory properties that could underlie the benefits associated with the folklore use of the plant, and may be acting through a suppression of mediators of inflammation.
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Hepatoprotective effect of the solvent fractions of the stem of Hoslundia opposita Vahl (Lamiaceae) against carbon tetrachloride- and paracetamol-induced liver damage in rats.
Peter A. Akah,Casmir I. Odo +1 more
TL;DR: The results suggest that the stem of Hoslundia opposita contains bioactive principles with hepatoprotective effect and showed good toxicity profile with an LD50 value above 5000 mg/kg for the methanol extract.
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Anti-plasmodial and anti-inflammatory activities of cyclotide-rich extract and fraction of Oldenlandia affinis (R. & S.) D.C. (Rubiaceae).
Chukwuemeka S. Nworu,Tochukwu Ifenyinwa Ejikeme,A. C. Ezike,O. O. Ndu,Theophine Chinwuba Akunne,Collins Azubuike Onyeto,Paul Okpalanduka,Peter A. Akah +7 more
TL;DR: Findings could explain, at least in part, the successes reported in the use of the herb, Oldenlandia affinis in the traditional treatment of malaria fever.
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Activation of murine lymphocytes and modulation of macrophage functions by fractions of Alchornea cordifolia (Euphorbiaceae) leaf extract
Chukwuemeka S. Nworu,Vladimir Temchura,Festus B. C. Okoye,Peter A. Akah,Charles O. Esimone,Klaus Überla +5 more
TL;DR: Strong immunomodulatory activities of A. cordifolia leaf extracts are demonstrated which could explain some of the therapeutic benefits attributed to the plant in traditional medicine and could also be exploited as a source of novel immunoregulating substances.