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Peter F. Crookes

Researcher at University of Southern California

Publications -  132
Citations -  8236

Peter F. Crookes is an academic researcher from University of Southern California. The author has contributed to research in topics: Esophageal disease & Esophagus. The author has an hindex of 47, co-authored 132 publications receiving 7934 citations. Previous affiliations of Peter F. Crookes include St. Vincent's Health System.

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ERCC1 mRNA levels complement thymidylate synthase mRNA levels in predicting response and survival for gastric cancer patients receiving combination cisplatin and fluorouracil chemotherapy.

TL;DR: Either ERCC1 or TS mRNA levels in a primary gastric adenocarcinoma has a statistically significant relationship to response; in this cohort TS RNA levels did not reach statistically significant association with survival as in the previous publication.
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Laparoscopic repair of large type III hiatal hernia: objective followup reveals high recurrence rate.

TL;DR: Laroscopic repair of type III hiatal hernias is associated with a disturbingly high (42%) prevalence of recurrent hernia and more than half such recurrences have few, if any, symptoms.
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Thymidylate synthase mRNA level in adenocarcinoma of the stomach: a predictor for primary tumor response and overall survival.

TL;DR: The genetic expression of TS (TSmRNA level) influences response to 5FU-based chemotherapy and survival for a cohort of patients with primary gastric cancer, and could lead to therapeutic decisions based on specific molecular properties within a tumor.
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Multivariate analysis of factors predicting outcome after laparoscopic Nissen fundoplication.

TL;DR: 24-hour pH monitoring provides the strongest outcome predictor of laparoscopic Nissen fundoplication and that outcome is based more on the correct identification of the disease than on its severity.
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Inflammation and specialized intestinal metaplasia of cardiac mucosa is a manifestation of gastroesophageal reflux disease.

TL;DR: The findings of cardiac mucosa, carditis, and intestinal metaplasia in an endoscopically normal-appearing gastroesophageal junction are histologic indicators of gastroeastern reflux disease and contribute to the authors understanding of the pathophysiology of the disease process.