P
Peter J. Newman
Researcher at Medical College of Wisconsin
Publications - 195
Citations - 16216
Peter J. Newman is an academic researcher from Medical College of Wisconsin. The author has contributed to research in topics: Platelet & Endothelial stem cell. The author has an hindex of 69, co-authored 191 publications receiving 15463 citations. Previous affiliations of Peter J. Newman include University of Texas Health Science Center at San Antonio & University of Oklahoma Health Sciences Center.
Papers
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Journal ArticleDOI
PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily
Peter J. Newman,Michael C. Berndt,Jack Gorski,Gilbert C. White,Suzanne Lyman,Cathy Paddock,William A. Muller +6 more
TL;DR: An antibody to a platelet integral membrane glycoprotein was found to cross-react with the previously identified CD31 myelomonocytic differentiation antigen and with hec7, an endothelial cell protein that is enriched at intercellular junctions.
Journal ArticleDOI
Molecular and cellular properties of PECAM-1 (endoCAM/CD31): a novel vascular cell-cell adhesion molecule.
TL;DR: It is demonstrated that PECAM-1 mediates cell-cell adhesion and support the idea that it may be involved in some of the interactive events taking place during thrombosis, wound healing, and angiogenesis.
Journal ArticleDOI
Integrins: dynamic scaffolds for adhesion and signaling in platelets.
TL;DR: An understanding that alphaIIbbeta3 functions as a dynamic molecular scaffold for extracellular and intracellular proteins has translated into diagnostic and therapeutic insights relevant to hematology and cardiovascular medicine, and further advances can be anticipated.
Journal ArticleDOI
The human platelet alloantigens, PlA1 and PlA2, are associated with a leucine33/proline33 amino acid polymorphism in membrane glycoprotein IIIa, and are distinguishable by DNA typing.
TL;DR: The ability to perform DNA-typing analysis for PlA phenotype may have a number of useful clinical applications, including fetal testing and determination of the phenotype of severely thrombocytopenic individuals.