P
Peter W. Jones
Researcher at Keele University
Publications - 327
Citations - 19716
Peter W. Jones is an academic researcher from Keele University. The author has contributed to research in topics: Population & Genotype. The author has an hindex of 76, co-authored 324 publications receiving 18761 citations. Previous affiliations of Peter W. Jones include University Hospital of Wales & University of Birmingham.
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Journal Article
Association of glutathione S-transferase GSTM1 and GSTT1 null genotypes with clinical outcome in epithelial ovarian cancer.
R. E. J. Howells,Charles W.E. Redman,K. K. Dhar,Panos Sarhanis,C. Musgrove,Peter W. Jones,Julie Alldersea,Anthony A. Fryer,Paul R. Hoban,Richard C. Strange +9 more
TL;DR: The combination of GSTM1 null/GSTT1 null is associated with outcome because of its influence on response to chemotherapy, and these preliminary findings may provide a basis for the selection of patients for treatment with chemotherapeutic agents.
Journal Article
Randomised, cross-over, placebo controlled trial of magnesium citrate in thetreatment of chronic persistent leg cramps.
TL;DR: In this paper, the authors tested whether magnesium citrate is effective in the treatment of leg cramps in non-pregnant individuals by conducting in a randomised, double-blind, cross-over placebo-controlled trial.
Journal ArticleDOI
Is the provision of information leaflets before colposcopy beneficial? A prospective randomised study.
R. E. J. Howells,P. D. J. Dunn,T. Isasi,R. Chenoy,E. Calvert,Peter W. Jones,J. Foden Shroff,C. W. E. Redman +7 more
TL;DR: An assessment of the usefulness of a leaflet distributed to women before colposcopy designed to reduce their anxiety and psychosexual by providing information.
Journal ArticleDOI
Susceptibility to Melanoma: Influence of Skin Type and Polymorphism in the Melanocyte Stimulating Hormone Receptor Gene
Fumiyo Ichii-Jones,John T. Lear,A.H.M. Heagerty,Andrew G. Smith,Peter E. Hutchinson,J.E. Osborne,Bill Bowers,Peter W. Jones,E. J. Davies,William E R Ollier,Wendy Thomson,Lillian Yengi,Joanna Bath,Anthony A. Fryer,Richard C. Strange +14 more
TL;DR: The data presented is interpreted as indicating that polymorphism at MC1R does not appear a major determinant of skin type, at least in terms of these allelic variants, which are not susceptibility candidates for malignant melanoma.
Journal ArticleDOI
Epithelial ovarian cancer: influence of polymorphism at the glutathione S -transferase GSTM1 and GSTT1 loci on p53 expression
P. Sarhanis,Charles W.E. Redman,Christopher W. Perrett,Brannigan K,Richard N. Clayton,P. Hand,C. Musgrove,V. Suarez,Peter W. Jones,Anthony A. Fryer,William E. Farrell,Richard C. Strange +11 more
TL;DR: The data are compatible with the view that GSTM1 and GSTT1 are critical in the detoxification of the products of oxidative stress produced during the repair of the ovarian epithelium and failure to detoxify products of this stress may result in damage to various genes in the host cell, including to p53, resulting in persistent expression of mutant protein.