P
Peter Wendelboe Hansen
Researcher at Aarhus University
Publications - 6
Citations - 164
Peter Wendelboe Hansen is an academic researcher from Aarhus University. The author has contributed to research in topics: Antigen & Cytotoxic T cell. The author has an hindex of 5, co-authored 6 publications receiving 164 citations.
Papers
More filters
Journal ArticleDOI
Isolation of human T and B lymphocytes by E-rosette gradient centrifugation. Characterization of the isolated subpopulations☆
TL;DR: Treatment of sheep red blood cells with 2-aminoethylisothiouronium bromide with AET accelerates and enhances E-rosette formation providing an effective and time saving method which takes less than 2 h to perform.
Journal ArticleDOI
Cell-mediated PPD-specific cytotoxicity against human monocyte targets: evidence for restriction by class II HLA antigens
Peter Wendelboe Hansen,M. Madsen,S E Christiansen,Hans Erik Johnsen,Flemming Kissmeyer-Nielsen +4 more
TL;DR: The results indicate that cell-mediated PPD specific cytotoxic cells have been detected in cultures of peripheral blood mononuclear cells stimulated for 6 days with PPD and indicates that the restriction element in this system in all probability is a class II antigen.
Journal ArticleDOI
Cell mediated PPD specific cytotoxicity against human monocyte targets: III. Cellular typing with CTLs restricted by class II HLA antigens.
TL;DR: The findings indicate that the bulk CTLs predominantly contain clones restricted by determinants strongly associated to the serologically defined HLA-DR antigens, which is in contrast to previous finding that PPD-specific C TLs are restricted by Hla-class II - and not by class IAntigens.
Journal ArticleDOI
Functional studies on lymphocytes from two siblings with congenital hypogammaglobulinaemia.
TL;DR: The results demonstrate a primary B cell defect in the patients and indicate an impaired cooperation between patients' B and T cells and indicate the presence of proliferating T cells in patients' PBL subpopulations.
Journal ArticleDOI
Cell mediated PPD specific cytotoxicity against human monocyte targets: II. IL-2 expansion improves the strength and discriminatory power of CTLs used for cellular typing
TL;DR: Large batches of Cytotoxic T Lymphocytes specific for antigenic components of Purified Protein Derivative of tuberculin were generated from 20 donors and it was found that CTLs could be cryopreserved without loss of activity, and compared to generating C TLs in primary culture alone, IL-2 expanded CTL's were stronger and discriminated better.