Showing papers by "Philippe Maingon published in 2002"
TL;DR: A better quality of the CT images, use of urethral opacification, and consensual definition of clinical target volumes and organs at risk may contribute to that improvement.
Abstract: The delineation of target volume and organs at risk depends on the organs definition, and on the modalities for the CT-scan acquisition. Inter-observer variability in the delineation may be large, especially when patient's anatomy is unusual. During the two french multicentric studies of conformal radiotherapy for localized prostate cancer, it was made an effort to harmonize the delineation of the target volumes and organs at risk. Two cases were proposed for delineation during two workshops. In the first case, the mean prostate volume was 46.5 mL (extreme: 31.7-61.3), the mean prostate and seminal vesicles volume was 74.7 mL (extreme: 59.6-80.3), the rectal and bladder walls varied respectively in proportion from 1 to 1.45 and from 1 to 1.16; in the second case, the mean prostate volume was 53.1 mL (extreme: 40.8-73.1), the volume of prostate plus seminal vesicles was 65.1 mL (extreme: 53.2-89), the rectal wall varied proportionally from 1 to 1, 24 and the vesical wall varied from 1 to 1.67. For participating centers to the french studies of dose escalation, a quality control of contours was performed to decrease the inter-observer variability. The ways to reduce the discrepancies of volumes delineation, between different observers, are discussed. A better quality of the CT images, use of urethral opacification, and consensual definition of clinical target volumes and organs at risk may contribute to that improvement.
15 citations
TL;DR: La mise au point presente des moyens de reduire ces ecarts en ameliorant les conditions d’acquisition des images and des contours des structures ainsi que the definition des volumes pertinents.
Abstract: Resume Au cours des deux etudes francaises multicentriques de radiotherapie conformationnelle pour le traitement du cancer localise de la prostate, une partie des efforts d’harmonisation a porte sur le contour des volumes-cibles et des organes critiques. Deux dossiers de malades ont ete soumis a des ateliers. Dans le premier cas, le volume prostatique moyen etait de 46,5 cm3 (extremes : 31,7-61,3), le volume elargi aux vesicules seminales moyen etait de 74,7 cm3 (extremes : 59,6-80,3), les volumes des parois rectale et vesicales variaient respectivement, en proportion de 1 a 1,45 et de 1 a 1,16. Dans le second cas, le volume moyen de la prostate etait de 53,1cm3, le volume de la prostate et des vesicules seminales etait de 65,1 cm3 (extremes : 53,2-89), la paroi rectale variant en proportion de 1 a 1,24, la paroi vesicale variant de 1 a 1,67. A la suite de ces ateliers, un controle de qualite des contours dans chaque centre participant a l’etude a permis d’eviter des divergences trop importantes entre les investigateurs. La mise au point presente des moyens de reduire ces ecarts en ameliorant les conditions d’acquisition des images et des contours des structures ainsi que la definition des volumes pertinents.
9 citations
TL;DR: The mesorectal space is the usual field for the spread of rectal cancers cells and it could therefore be considered as the clinical target volume (CTV) in the preoperative conformational radiotherapy as discussed by the authors.
Abstract: Preoperative radiotherapy is the standard treatment for locally advanced resectable rectal adenocarcinoma. The total mesorectal excision leads to a dramatic increase of local control rate. Thus, the mesorectal space is the usual field for the spread of rectal cancers cells. It could therefore be considered as the clinical target volume (CTV) in the preoperative conformational radiotherapy. From the anatomical basis and radiological contributions, we propose several CTVs for different locations of rectal carcinoma.
8 citations
TL;DR: Dans cet article de generalites sont discutees les difficultes de l’evaluation du volume tumoral macroscopique and du volume cible anatomoclinique, la representation des differents volumes selon les recommandations du rapport ICRU 62, les principales discordances inter-observateurs lors oficiales de la definition des volumes.
Abstract: Resume Le contour des volumes cibles est une etape medicale dans la preparation des radiotherapies de conformation. Dans cet article de generalites sont discutees les difficultes de l’evaluation du volume tumoral macroscopique (GTV) et du volume cible anatomoclinique (CTV), la representation des differents volumes selon les recommandations du rapport ICRU 62, les principales discordances inter-observateurs lors de la definition des volumes.
4 citations
3 citations
Journal Article•
1 citations