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Philippe Moreillon
Researcher at University of Lausanne
Publications - 78
Citations - 2966
Philippe Moreillon is an academic researcher from University of Lausanne. The author has contributed to research in topics: Staphylococcus aureus & Streptococcus gordonii. The author has an hindex of 33, co-authored 78 publications receiving 2777 citations. Previous affiliations of Philippe Moreillon include University Hospital of Lausanne.
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Expression of Staphylococcus aureus clumping factor A in Lactococcus lactis subsp. cremoris using a new shuttle vector.
TL;DR: These experiments provide a new way to study individual staphylococcal pathogenic factors and might complement both classical knockout mutagenesis and modern in vivo expression technology and signature tag mutagenisation.
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Staphylococcus aureus host range and human-bovine host shift.
Olga Sakwinska,Marlyse Giddey,Martine Moreillon,Delphine Morisset,Andreas Waldvogel,Philippe Moreillon +5 more
TL;DR: Results suggest that host specificity is a lineage-specific trait that can rapidly evolve and suggest that the emergence of the new bovine-adapted genotype was due to a recent host shift from humans to cows concurrent with a loss of the ability to colonize humans.
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Beta-lactams against methicillin-resistant Staphylococcus aureus.
TL;DR: In this article, anti-PBP2A beta-lactams with over 10-fold greater penicillin-binding protein 2A affinities and low minimal inhibitory concentrations were developed, primarily in the cephem and carbapenem classes.
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Experimental and computational approaches to quantitative proteomics: status quo and outlook.
TL;DR: Special emphasis is placed on quantification techniques: gel-based, and label-free techniques are briefly discussed whereas stable-isotope coding and internal peptide standards are extensively reviewed.
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High-Dose Daptomycin plus Fosfomycin Is Safe and Effective in Treating Methicillin-Susceptible and Methicillin-Resistant Staphylococcus aureus Endocarditis
José M. Miró,José M. Entenza,Ana del Río,María Velasco,Ximena Castañeda,Cristina Garcia de la Maria,Marlyse Giddey,Yolanda Armero,Juan M. Pericàs,Carlos Cervera,Carlos A. Mestres,Manuel Almela,Carlos Falces,Francesc Marco,Philippe Moreillon,Asunción Moreno +15 more
TL;DR: This combination was tested in vitro against 7 MSSA, 5 MRSA, and 2 intermediately glycopeptide-resistant S. aureus isolates and proved to be synergistic against 11 (79%) strains and bactericidal against 8 (57%) strains.