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Phillip Kotkes
Researcher at Tel Aviv University
Publications - 4
Citations - 328
Phillip Kotkes is an academic researcher from Tel Aviv University. The author has contributed to research in topics: Complementary DNA & Gene. The author has an hindex of 3, co-authored 4 publications receiving 328 citations.
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Journal ArticleDOI
Human epithelial tumor antigen cDNA sequences. Differential splicing may generate multiple protein forms.
Daniel H. Wreschner,Mara Hareuveni,Ilan Tsarfaty,Nechama I. Smorodinsky,Judith Horev,Joseph Z. Zaretsky,Phillip Kotkes,Mordechai Weiss,Richard Lathe,Arnold Dion,Iafa Keydar +10 more
TL;DR: The cDNAs and deduced amino acid sequences, presented here, define the complete amino acids sequences of the epithelial tumor antigen and demonstrate the existence of multiple protein forms that probably localize to different cellular and extracellular compartments.
Journal ArticleDOI
A transcribed gene, containing a variable number of tandem repeats, codes for a human epithelial tumor antigen. cDNA cloning, expression of the transfected gene and over-expression in breast cancer tissue.
Mara Hareuveni,Ilan Tsarfaty,Joseph Z. Zaretsky,Phillip Kotkes,Judith Horev,Sheila Zrihan,Mordechai Weiss,Stephen Green,Richard Lathe,Iafa Keydar,Daniel H. Wreschner +10 more
TL;DR: The above studies unequivocally establish the over-expression of a VNTR gene coding for an epithelial tumor antigen in human breast cancer tissue.
Isolation and characterization of full length cDNA coding for the H23 breast tumor associated antigen
Daniel H. Wreschner,Ilan Tsarfaty,M. Hareuveni,Joseph Z. Zaretsky,Nechama I. Smorodinsky,Mordechai Weiss,Judith Horev,Phillip Kotkes,S. Zrihan,J. M. Jeltsch,S. Green,R. Lathe,Iafa Keydar +12 more
TL;DR: H23 monoclonal antibody specifically recognizes a breast tumor associated antigen and was used to isolate cDNA insert that codes for the antigenic epitope.
Book ChapterDOI
Molecular Analysis of H23 Epithelial Tumor Antigen - Differentially Spliced Full Length cDNAs and Gene
Daniel H. Wreschner,Ilan Tsarfaty,Mara Hareuveni,Joseph Z. Zaretsky,Nechama I. Smorodinsky,S. Zrihan,M. Burstein,Judith Horev,Phillip Kotkes,Iafa Keydar,Mordechai Weiss,Richard Lathe,C. A. Hart,K. McCarthy,Charlene J. Williams,A.S. Dion +15 more
TL;DR: The isolation and characterization of the complementary DNAs and gene which code for an epithelial tumor antigen (H23-ETA), aberrantly expressed in human breast tumor tissue, are described here, and reverse PCR indicates that the relative ratios of the alternatively spliced forms vary in different epithelial tissues.