P
Piet de Kleijn
Researcher at Utrecht University
Publications - 14
Citations - 422
Piet de Kleijn is an academic researcher from Utrecht University. The author has contributed to research in topics: Haemophilia & Von Willebrand disease. The author has an hindex of 7, co-authored 14 publications receiving 350 citations. Previous affiliations of Piet de Kleijn include University Medical Center Utrecht.
Papers
More filters
Journal ArticleDOI
The effects of postponing prophylactic treatment on long-term outcome in patients with severe hemophilia.
Krista Fischer,Johanna G. van der Bom,Eveline P. Mauser-Bunschoten,Goris Roosendaal,Robert Prejs,Piet de Kleijn,Diederick E. Grobbee,Marijke van den Berg +7 more
TL;DR: The effect of postponing prophylaxis on long-term arthropathy was studied in a cohort of 76 patients with severe hemophilia born between 1965 and 1985, finding that most patients have their first joint bleed after the age of 2 years.
Journal ArticleDOI
Discontinuing early prophylaxis in severe haemophilia leads to deterioration of joint status despite low bleeding rates
A. Nijdam,Wouter Foppen,Piet de Kleijn,Evelien P. Mauser-Bunschoten,Goris Roosendaal,Karin P M van Galen,Roger E. G. Schutgens,Yvonne T. van der Schouw,Krista Fischer +8 more
TL;DR: Results support continuation of long-term prophylaxis in adults and demonstrate the need for objective monitoring of joint status.
Journal ArticleDOI
Measurement of joint health in persons with haemophilia: A systematic review of the measurement properties of haemophilia-specific instruments
Samantha C. Gouw,Merel A. Timmer,Alok Srivastava,Piet de Kleijn,P. Hilliard,Marjolein Peters,Victor S. Blanchette,Krista Fischer +7 more
TL;DR: Several haemophilia‐specific measurement tools are available, but an overview of the measurement properties is lacking and an accurate assessment of joint health in persons with ha Hemophilia is crucial.
Journal ArticleDOI
Long-term impact of joint bleeds in von Willebrand disease: A nested case-control study
Karin P M van Galen,Piet de Kleijn,Wouter Foppen,J. Eikenboom,Karina Meijer,Roger E. G. Schutgens,Krista Fischer,Marjon H. Cnossen,Joke de Meris,Karin Fijnvandraat,Johanna G. van der Bom,Britta A P Laros-van Gorkom,Frank W.G. Leebeek,Eveline P. Mauser-Bunschoten +13 more
TL;DR: In conclusion, arthropathy occurs in 40% of VWD patients after joint bleeds and is associated with pain, radiological abnormalities, functional limitations, and less social participation (Dutch trial register: NTR4548).
Journal ArticleDOI
Sports participation and sports injuries in Dutch boys with haemophilia
Olav Versloot,Merel A. Timmer,Piet de Kleijn,Marleen Schuuring,Casper F. van Koppenhagen,Janjaap van der Net,Krista Fischer +6 more
TL;DR: Sports participation in children with hemophilia is generally thought to be associated with increased injury risk, which is generally considered highest in severe hemophiliac children.