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Piyush Trivedi

Researcher at Rajiv Gandhi Proudyogiki Vishwavidyalaya

Publications -  124
Citations -  2146

Piyush Trivedi is an academic researcher from Rajiv Gandhi Proudyogiki Vishwavidyalaya. The author has contributed to research in topics: Quantitative structure–activity relationship & Apoptosis. The author has an hindex of 20, co-authored 120 publications receiving 1701 citations. Previous affiliations of Piyush Trivedi include Shri Govindram Seksaria Institute of Technology and Science & Poona College of Arts Science & Commerce.

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Journal Article

QSAR studies of cytotoxic acridine 5,7-diones : A comparative study using P-VSA descriptors and topological descriptors

N. S. Hari Narayana Moorthy, +2 more
- 01 Jan 2007 - 
TL;DR: The result of the QSAR study suggests the presence of hydrophobic moieties in the molecule and is conducive for the cytotoxic activity of the acridine 5,7-diones whereas increase in molecular surface area bearing a fractional negative charge is detrimental to the biological activity.
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Analysis of surface area features of structurally diverse molecules for Bcr/Abl kinase inhibitory activity and antiproliferative activity

N. S. Hari Narayana Moorthy, +4 more
- 01 May 2014 - 
TL;DR: In the present investigation, structurally different compounds possessing Bcr/Abl kinase inhibitory activity and antiproliferative activity against K562 cell lines were used for the structural analysis and the correlations developed between the TPSA, logP and activities showed that the compounds have increased T PSA values possessed better B Cr/A Bl kinase inhibition activity, while those compounds have moderate logP values.
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Design, in vitro evaluation and in vivo studies of novel delayed release tablets of pantoprazole

Pooja Choudhry, +7 more
- 01 Dec 2012 - 
TL;DR: In this paper, a simple, direct compression delayed release formulation consisting of pantoprazole was investigated in an effort to reduce production costs, in which Opadry and Acryl-EZE systems have been utilized for subcoating and enteric coating respectively.
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Synthesis, Characterization, Biological Evaluation and Docking of Coumarin Coupled Thiazolidinedione Derivatives and its Bioisosteres as PPARγ Agonists

Shubhanjali Shukla, +6 more
- 31 Aug 2012 - 
TL;DR: A new series of coumarin coupled thiazolidinedione derivatives and its bioisosters (oxazolidiningione and imidazolidine nucleus) were synthesized by Knoevenagel condensation of 4-((7-hydroxy-2-oxo-2H-chromen-4-yl) methoxy) benzaldehyde with 2,4 thiazolicinedione and itsBioisosteres.
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Quantitative Structure Activity Relationship Studies of Piperazinyl Phenylalanine Derivatives as VLA-4/VCAM-1 Inhibitors

Dinesh Bhargava, +3 more
- 31 Aug 2009 - 
TL;DR: The result of the study suggests that the chlorine atoms in the molecule and fourth order fragmentation patterns in the molecular skeleton favour VLA-4/VCAM-1 inhibition shown by the title compounds whereas lipophilicity and nitrogen bonded to aromatic bond are not conducive for VLA/VCam-1 inhibitory activity.