Prajwal Paudel

TL;DR: This work examines the biological activity of essential oils of Cinnamomum camphora leaves, C. glaucescens fruit, and C. tamala root from Nepal for phytotoxic activity against lettuce and perennial ryegrass, brine shrimp lethality, and antibacterial, antifungal, cytotoxic, insecticidal, and nematicidal activities.

TL;DR: The DFT results reveal that the C-P bond could be cleaved by water, OH- or •OH, with the energy barrier opposing bond dissociation being lowest in the presence of the radical species, and that C-N bond cleavage is favored by the formation of both nitrogen- and carbon-centered radicals.

TL;DR: The bioactivity of P. roxburghii essential oil is consistent with its traditional medicinal use and exhibits anti-bacterial activity and anti-fungal activity against Aspergillus niger.

TL;DR: DFT calculations (B3LYP/6-31G*) revealed thermal decomposition of ascaridole to be energetically accessible at hydrodistillation and GC conditions, but these are spin-forbidden processes, so decomposition likely proceeds by way of homolytic peroxide bond cleavage rather than retro-Diels-Alder elimination of molecular oxygen.

TL;DR: The structure model and biochemical data suggest that the USP9X catalytic domain harbors three Ub binding sites, and a zinc finger in the fingers subdomain and the β-hairpin insertion both play important roles in polyUb chain processing and linkage specificity.