Prakash Parajuli

TL;DR: In this article, 3-hydroxyflavone was selected as a probe for in vitro glycorandomization of all flavonols using diverse nucleotide diphosphate-d/l-sugars.

TL;DR: This multi-monocistronic synthetic vector in a microbial platform is customizable to defined task and would certainly be useful for applications in producing and modifying such therapeutically valued plant secondary metabolites.

TL;DR: Epothilone A 7-O-β-D-glucoside was structurally elucidated by ultra-high performance liquid chromatography-photo diode array conjugated with high resolution quantitative time-of-flight-electrospray ionization mass spectroscopy (HR-QTOF ESI-MS/MS) supported by one-and two-dimensional nuclear magnetic resonance studies.

TL;DR: Two plant-originated C-glucosyltransferases from Glycine max and Gentiana triflora were accessed for glucosylation of selected flavones chrysin and luteolin, found to be more soluble and more stable to high temperature, different pH range, and β- glucosidase enzyme, than O-glUCosylated derivative of chrysIn.

TL;DR: A synthetic vector system using different promoters has been developed and used for the synthesis of C3G in E. coli BL21 (DE3) by directing the metabolic flux towards the UDP-d-glucose.