P
Prapon Wilairat
Researcher at Mahidol University
Publications - 151
Citations - 5127
Prapon Wilairat is an academic researcher from Mahidol University. The author has contributed to research in topics: Plasmodium falciparum & Gene. The author has an hindex of 34, co-authored 138 publications receiving 4752 citations. Previous affiliations of Prapon Wilairat include Australian National University & University of Oregon.
Papers
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Journal ArticleDOI
Simple and Inexpensive Fluorescence-Based Technique for High-Throughput Antimalarial Drug Screening
TL;DR: A side-by-side comparison of this new fluorescence assay and a standard radioisotopic method suggest that it may be an ideal method for high-throughput antimalarial drug screening.
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Antimalarial Alkoxylated and Hydroxylated Chalones: Structure−Activity Relationship Analysis
TL;DR: Chalcones with 2',3' ',4' '-trimethoxy, 2'',4' -dimethoxy and 4'-hydroxy groups on ring B were synthesized and evaluated in vitro against Plasmodium falciparum (K1) in a [3H] hypoxanthine uptake assay as discussed by the authors.
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Structure-activity relationships of antileishmanial and antimalarial chalcones.
TL;DR: Visualization of the steric and electrostatic fields generated from comparative molecular field analysis (CoMFA) indicate that the ring A of chalcones make a more significant contribution to antileishmanial activity while both rings A and B are important for antimalarial activity.
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Antimalarial activity of ferrocenyl chalcones.
TL;DR: A series of ferrocenyl chalcones were synthesized and evaluated for in vitro antimalarial activity against a chloroquine-resistant strain of Plasmodium falciparum and differences in activity were not readily explained by the size and lipophilicity characteristics of these compounds.
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Severity differences in β‐thalassaemia/haemoglobin E syndromes: implication of genetic factors
Winichagoon P,Varaporn Thonglairoam,Suthat Fucharoen,Prapon Wilairat,Yasuyuki Fukumaki,P. Wasi +5 more
TL;DR: Increased expression of the Gγ‐globin gene and higher production of haemoglobin F. which could reduce the overall globin chain imbalance, were also associated with homozygosity for the Xmn I cleavage site and thus with less severe anaemia, however, this effect was not seen inXmn I site heterozygotes.