Prasad V. Bharatam

TL;DR: N-Fused aminoimidazoles showed potent anticancer activities in kidney and breast cancer cell lines, low toxicity to normal cells, relatively higher potency compared to etoposide and 5-fluorouracil in kidney cancer cell Lines, and potent inhibition in cell migration.

TL;DR: It was found that rifampicin in commercial bulk samples exist as various combinations of form I, form II and amorphous, and as physical forms show comparable intrinsic dissolution rate (IDR) at all the pH values, solubility advantage associated with rifampsicin polymorphs is negligible.

TL;DR: Ab initio density functional theory calculations on model monomeric and dimeric complexes of the simplest thiosemicarbazone have revealed that monomers and halogen-bridged dimers have similar stability and that sulfur-bridges dimers are stable only when halogen atoms are engaged in hydrogen bonding with the solvent of crystallization or H2O molecules.

TL;DR: The molecular electrostatic potential (MESP) surfaces of neutral, protonated, and deprotonated biguanide have been shown to be similar in their most stable arrangements and the most stable structure of the importantbiguanide derivatives has been given after performing a conformational search.

TL;DR: This tool is a versatile tool which can be easily used to generate other dendrimer structures with different chemistry and topology and integrate this tool easily with the widely used molecular dynamics software AMBER.