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Prasanna Hariharan
Researcher at Center for Devices and Radiological Health
Publications - 50
Citations - 1094
Prasanna Hariharan is an academic researcher from Center for Devices and Radiological Health. The author has contributed to research in topics: Particle image velocimetry & Imaging phantom. The author has an hindex of 16, co-authored 46 publications receiving 849 citations. Previous affiliations of Prasanna Hariharan include University of Cincinnati & Food and Drug Administration.
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Journal ArticleDOI
Assessment of CFD Performance in Simulations of an Idealized Medical Device: Results of FDA’s First Computational Interlaboratory Study
Sandy F. C. Stewart,Eric G. Paterson,Greg W. Burgreen,Prasanna Hariharan,Matthew Giarra,Varun Reddy,Steven W. Day,Keefe B. Manning,Steven Deutsch,Michael R. Berman,Matthew R. Myers,Richard A. Malinauskas +11 more
TL;DR: In this article, the authors conducted a computational interlaboratory study to determine the suitability and methodology for simulating fluid flow in an idealized medical device, which was a cylindrical nozzle with a conical collector and sudden expansion on either side of a 0.04 m long, 0.004 m diameter throat.
Journal ArticleDOI
Multilaboratory Particle Image Velocimetry Analysis of the FDA Benchmark Nozzle Model to Support Validation of Computational Fluid Dynamics Simulations
Prasanna Hariharan,Matthew Giarra,Varun Reddy,Steven W. Day,Keefe B. Manning,Steven Deutsch,Sandy F. C. Stewart,Matthew R. Myers,Michael R. Berman,Greg W. Burgreen,Eric G. Paterson,Richard A. Malinauskas +11 more
TL;DR: In this paper, the authors evaluate the use and limitations of computational fluid dynamics (CFD) in assessing blood flow parameters related to medical device safety, including mean velocity and turbulent flow quantities.
Journal ArticleDOI
FDA Benchmark Medical Device Flow Models for CFD Validation.
Richard A. Malinauskas,Prasanna Hariharan,Steven W. Day,Luke H. Herbertson,Martin Buesen,Ulrich Steinseifer,Kenneth I. Aycock,Bryan C. Good,Steven Deutsch,Keefe B. Manning,Brent A. Craven +10 more
TL;DR: The primary goal of this article is to summarize the FDA initiative and to report recent findings from the benchmark blood pump model study, which aided the development of an FDA Guidance Document on factors to consider when reporting computational studies in medical device regulatory submissions.
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Peristaltic transport of non-Newtonian fluid in a diverging tube with different wave forms
TL;DR: It is observed that, even for zero flow rate, reflux occurs near the tube wall and the thickness and shape of the reflux region strongly depends on @f, n, and shape Of all the wave shapes considered, @DP"L"m"a"x obtained is maximum for the square wave and minimum for the triangular wave.
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HIFU procedures at moderate intensities--effect of large blood vessels.
TL;DR: A three-dimensional computational model is presented for studying the efficacy of high-intensity focused ultrasound (HIFU) procedures targeted near large blood vessels and suggests that optimally focused transducers can generate lesions that are significantly larger than the ones produced by highly focused beams.