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Prodromos Sidiropoulos

Researcher at University of Crete

Publications -  192
Citations -  6100

Prodromos Sidiropoulos is an academic researcher from University of Crete. The author has contributed to research in topics: Rheumatoid arthritis & Internal medicine. The author has an hindex of 36, co-authored 162 publications receiving 5237 citations. Previous affiliations of Prodromos Sidiropoulos include University of Bern & National and Kapodistrian University of Athens.

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Expansion of toll-like receptor 9-expressing B cells in active systemic lupus erythematosus: implications for the induction and maintenance of the autoimmune process.

TL;DR: In patients with active SLE, the proportion of peripheral blood memory B cells and plasma cells expressing TLR-9 is increased and endogenous nucleic acids released during apoptotic cell death may stimulate B cells via TLr-9 and contribute to SLE pathogenesis.
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Lessons learned from anti-CD40L treatment in systemic lupus erythematosus patients.

TL;DR: In view of the significant immunomodulatory effects of anti-CD40L treatment in patients with lupus nephritis, the increasing realization of the importance of premature atherosclerosis in l upus and an increasing amount of data supporting a role for the CD40-CD 40L interactions in this process, inhibition of this pathway deserves further exploration in lupu.
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Anti-tumor necrosis factor therapy improves insulin resistance, beta cell function and insulin signaling in active rheumatoid arthritis patients with high insulin resistance

TL;DR: Anti-TNF therapy improved insulin sensitivity and reversed defects in the insulin signaling cascade in RA patients with active disease and high insulin resistance, and was effective in modifying cardiovascular disease burden in active RA patients.