P
PT Pearce
Publications - 1
Citations - 1601
PT Pearce is an academic researcher. The author has contributed to research in topics: 11β-hydroxysteroid dehydrogenase type 1 & Receptor. The author has an hindex of 1, co-authored 1 publications receiving 1572 citations.
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Mineralocorticoid action: target tissue specificity is enzyme, not receptor, mediated
TL;DR: The presence of the enzyme 11 beta-hydroxy-steroid dehydrogenase, which converts cortisol and corticosterone, but not aldosterone, to their 11-keto analogs, means that these analogs cannot bind to mineralocorticoid receptors.