Q
Qiang Shen
Researcher at University of Texas Health Science Center at San Antonio
Publications - 59
Citations - 2600
Qiang Shen is an academic researcher from University of Texas Health Science Center at San Antonio. The author has contributed to research in topics: Cerebral blood flow & Magnetic resonance imaging. The author has an hindex of 28, co-authored 56 publications receiving 2309 citations. Previous affiliations of Qiang Shen include University of Massachusetts Medical School & University of Texas at San Antonio.
Papers
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Journal ArticleDOI
Tau protein aggregation is associated with cellular senescence in the brain.
Nicolas Musi,Nicolas Musi,Joseph M. Valentine,Kathryn R. Sickora,Eric Baeuerle,Cody S. Thompson,Qiang Shen,Miranda E. Orr,Miranda E. Orr +8 more
TL;DR: Using four AD transgenic mouse models, it is found that NFTs, but not Aβ plaques, display a senescence‐like phenotype, which contributes to neurodegeneration.
Journal ArticleDOI
Regional cerebral blood flow and BOLD responses in conscious and anesthetized rats under basal and hypercapnic conditions: implications for functional MRI studies.
Kenneth M. Sicard,Qiang Shen,Mathew E. Brevard,Ross Sullivan,Craig F. Ferris,Jean A. King,Timothy Q. Duong +6 more
TL;DR: Since CBF and BOLD responses were substantially higher under awake condition whereas blood gases were not statistically different, it was concluded that cerebrovascular reactivity was suppressed by anesthetics.
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Characterizing the diffusion/perfusion mismatch in experimental focal cerebral ischemia
Xiangjun Meng,Marc Fisher,Qiang Shen,Christopher H. Sotak,Christopher H. Sotak,Timothy Q. Duong +5 more
TL;DR: Following the evolution of the diffusion/ perfusion mismatch in permanent and 60‐ minute temporary focal experimental ischemia models in Sprague‐Dawley rats using the intraluminal middle cerebral artery occlusion (MCAO) method, there was a significant difference in 24‐ hour infarct volumes between the permanent and temporary occlusions groups.
Journal ArticleDOI
Pixel-by-Pixel Spatiotemporal Progression of Focal Ischemia Derived Using Quantitative Perfusion and Diffusion Imaging
TL;DR: Together, these results illustrate an analysis approach to systemically track the pixel-by-pixel spatiotemporal progression of acute ischemic brain injury and identify a potential therapeutic window.
Journal ArticleDOI
Functional, perfusion and diffusion MRI of acute focal ischemic brain injury
TL;DR: Comparison of the relative and absolute fMRI signal changes suggest caution when interpreting percent changes in disease states in which the baseline signals are physiologically altered; quantitative CBF fMRI are more appropriate measures.