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Qingqiang Yao

Researcher at Nanjing Medical University

Publications -  43
Citations -  808

Qingqiang Yao is an academic researcher from Nanjing Medical University. The author has contributed to research in topics: Cartilage & Lumbar. The author has an hindex of 13, co-authored 43 publications receiving 463 citations. Previous affiliations of Qingqiang Yao include University of California, Los Angeles.

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Design, construction and mechanical testing of digital 3D anatomical data-based PCL–HA bone tissue engineering scaffold

TL;DR: The combination of CT and CAD reverse technology could accomplish the design and manufacturing of complex bone tissue engineering scaffolds, with no significant difference in the impacts of the microstructures towards the physical properties of different porous scaffolds under large load.
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Endothelial ZEB1 promotes angiogenesis-dependent bone formation and reverses osteoporosis

TL;DR: It is shown that loss of ZEB1 in these cells epigenetically suppresses Notch signaling, leading to impaired angiogenesis and osteogenesis, and that Zeb1 delivery via liposomes ameliorates bone loss in osteoporotic mice.
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A multifunctional anti-inflammatory drug that can specifically target activated macrophages, massively deplete intracellular H2O2, and produce large amounts CO for a highly efficient treatment of osteoarthritis.

TL;DR: In vivo experiments confirmed that CPHs can massively deplete ROS in OA joints and effectively suppress the degradation of articular cartilage and their extracellular matrix and the high levels of CO generated in the joints do not result in notable changes in the HbCO levels in blood.
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Antimicrobial Activity of 3D-Printed Poly(ε-Caprolactone) (PCL) Composite Scaffolds Presenting Vancomycin-Loaded Polylactic Acid-Glycolic Acid (PLGA) Microspheres.

TL;DR: The 3D-printed, PDA-coated PCL scaffold carrying vancomycin-loaded PLGA microspheres exhibited good biocompatibility and a sustained antibacterial effect in vitro.
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Percutaneous kyphoplasty assisted with/without mixed reality technology in treatment of OVCF with IVC: a prospective study

TL;DR: PKP assisted with MR technology can accurately orientate the position of IVC area, which can be augmented by the balloon leading to more satisfied vertebral height improvement, cement diffusion, and pain relief.