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Qiongming Xu
Researcher at Soochow University (Suzhou)
Publications - 90
Citations - 1450
Qiongming Xu is an academic researcher from Soochow University (Suzhou). The author has contributed to research in topics: In vivo & Camellia oleifera. The author has an hindex of 19, co-authored 86 publications receiving 1010 citations. Previous affiliations of Qiongming Xu include University of Mississippi & Peking Union Medical College.
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Journal ArticleDOI
Antitumor activity of Pulsatilla chinensis (Bunge) Regel saponins in human liver tumor 7402 cells in vitro and in vivo.
Qiongming Xu,Zhan Shu,He Wenjun,Lanying Chen,Shilin Yang,Shilin Yang,Gang Yang,Yanli Liu,Xiaoran Li +8 more
TL;DR: Results suggested that P. chinensis saponins exert potential anticancer activity in treating tumors in nude mice and no toxic side effects.
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Dihydrotanshinone exhibits an anti-inflammatory effect in vitro and in vivo through blocking TLR4 dimerization.
Renyikun Yuan,Liting Huang,Lijun Du,Feng Jianfang,Jun Li,Ying-Ying Luo,Qiongming Xu,Shilin Yang,Hongwei Gao,Yulin Feng +9 more
TL;DR: Investigating the molecular mechanism of DHT indicated that TLR4‐MyD88‐NF‐&kgr;B/MAPK signaling cascades were involved in the anti‐inflammatory activity of D HT in vitro and in vivo, suggesting that DHT may be a potential therapeutic agent for inflammatory diseases.
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Total tanshinones exhibits anti-inflammatory effects through blocking TLR4 dimerization via the MyD88 pathway.
Hongwei Gao,Xin Liu,Wen Sun,Naixin Kang,Yanli Liu,Shilin Yang,Qiongming Xu,Chunming Wang,Xiuping Chen +8 more
TL;DR: TTN exerts anti-inflammatory effects in vitro and in vivo by blocking TLR4 dimerization to activate MyD88–TAK1–NF-κB/MAPK signaling cascades, which provide the molecular basis of the anti- inflammation effect of Danshen and suggest that TTN is a potential agent for the treatment of inflammatory diseases.
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Ginsenoside Rb1 exerts anti-inflammatory effects in vitro and in vivo by modulating toll-like receptor 4 dimerization and NF-kB/MAPKs signaling pathways.
TL;DR: In animal models, Rb1 markedly alleviated LPS- or cantharidin-induced acute kidney injury, rescued L PS-induced septic mice from death, and inhibited dimethyl benzene-induced mouse ear edema, suggesting Rb 1 represents an optimal molecule for treating inflammatory diseases.
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Tanshinones and diethyl blechnics with anti-inflammatory and anti-cancer activities from Salvia miltiorrhiza Bunge (Danshen).
Hongwei Gao,Wen Sun,Jianping Zhao,Xiaxia Wu,Jin-Jian Lu,Xiuping Chen,Qiongming Xu,Ikhlas A. Khan,Shilin Yang +8 more
TL;DR: The anti-cancer activity investigation indicated that most of isolated compounds exhibited cytotoxicity and the SAR analysis showed that the intact D ring was indispensable and unsaturated D ring played vital role.